Home-based and tele-rehabilitation for chronic respiratory diseases
Expanding Pulmonary Rehabilitation in Other Chronic Respiratory Disease Than COPD - the ExPuRe Pilot Study
This study tests if home-based and online rehabilitation programs can help people with chronic lung diseases feel better and be more active compared to those who just get regular care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 40 Years and up |
| Sex | All |
| Sponsor | Copenhagen University Hospital, Hvidovre Academic / other |
| Locations | 5 sites (Copenhagen, Greater Copenhagen and 4 other locations) |
| Trial ID | NCT06636487 on ClinicalTrials.gov |
What this trial studies
This pilot randomized clinical trial evaluates the effectiveness of structured home-based pulmonary rehabilitation (HPR) and supervised pulmonary tele-rehabilitation (PTR) for patients with chronic respiratory diseases such as idiopathic pulmonary fibrosis, sarcoidosis, bronchiectasis, and asthma. The study aims to assess patient willingness, acceptance, adherence, and the potential benefits of these rehabilitation methods on respiratory symptoms, quality of life, and physical activity. Participants will be compared to a control group receiving usual care to determine the impact of the interventions.
Who should consider this trial
Good fit: Ideal candidates include patients with chronic respiratory diseases who have a clinically assessed need for pulmonary rehabilitation and reside in the Capital Region of Copenhagen.
Not a fit: Patients who do not have a clinically assessed need for pulmonary rehabilitation or those who are unable to participate in the physical activities required may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve respiratory symptoms and quality of life for patients with chronic respiratory diseases.
How similar studies have performed: Other studies have shown promising results with home-based and tele-rehabilitation approaches for chronic respiratory diseases, suggesting potential for success in this study.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:
* Residency in the Capital Region of Copenhagen
* A clinically assessed need for pulmonary rehabilitation including respiratory symptoms, corresponding to MRC grade 2 or higher and where:
1. Center-based PR is not standard available or
2. Center-based PR being declined by the patient
* Able to stand up from a chair (height 44-46cm) and walk 10 meters independently (with or without a walking aid)
* Capable of lifting both arms to horizontal with at least 1 kg dumbbells in each hand
* And a minimum of one of the below mentioned diagnoses:
1. ILD (Interstitial lung disease, Idiopathic pulmonary fibrosis, Sarcoidosis):
DLCO lower than 80 % or FVC lower than 80%, HRCT verified, Age higher than 40 years, Confirmed respiratory physician diagnosis
2. Asthma:
With chronic airway obstruction, ACQ score higher than 1, FEV1 lower than 80%, Age higher than 50 years, Confirmed respiratory physician diagnosis of Asthma
3. Bronchiectasis:
FEV1 lower than 80%, HRCT verified, Age higher than 40 years, Confirmed respiratory physician diagnosis
Exclusion Criteria:
* Cognitive impairment - unable to follow instructions
* Impaired hearing or vision - unable to see or hear instruction from a tablet
* Unable to understand and speak Danish
* Comorbidities where the exercise content is contraindicated
Where this trial is running
Copenhagen, Greater Copenhagen and 4 other locations
- Copenhagen University Center, Amager — Copenhagen, Greater Copenhagen, Denmark (Recruiting)
- Copenhagen University Center, Frederiksberg-Bispebjerg — Copenhagen, Greater Copenhagen, Denmark (Recruiting)
- Copenhagen University Center, Hvidovre — Copenhagen, Greater Copenhagen, Denmark (Recruiting)
- Copenhagen University Center, Herlev-Gentofte — Gentofte, Greater Copenhagen, Denmark (Recruiting)
- Copenhagen University Center, Hillerød — Hillerød, Greater Copenhagen, Denmark (Recruiting)
Study contacts
- Principal investigator: Henrik Hansen, PhD, Msc, PT — Dept. of Respiratory Medicine, University Hospital Hvidovre
- Study coordinator: Henrik Hansen, PhD, PT
- Email: henrik.hansen.09@regionh.dk
- Phone: 4528946780
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.