HIV prevention program for Latino male couples

Connecting Latinos En Pareja: a Couples-based HIV Prevention Intervention for Latino Male Couples

Not applicable Interventional University of Central Florida · NCT06131931

This study is testing a program to help Latino male couples learn how to better protect themselves from HIV and see if it makes a difference over nine months.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment400 (estimated)
Ages18 Years to 100 Years
SexMale
SponsorUniversity of Central Florida Academic / other
Locations1 site (Orlando, Florida)
Trial IDNCT06131931 on ClinicalTrials.gov

What this trial studies

This intervention aims to evaluate the effectiveness of Connecting Latinxs en Pareja (CLP), a four-session program designed to increase HIV protection among Latino male couples. Participants will be recruited from high HIV burden areas and randomly assigned to either the CLP intervention or a Wellness Promotion control group. The study will track changes in HIV protective behaviors over nine months, utilizing both biological markers and self-reported data. All sessions will be conducted remotely via Zoom, ensuring accessibility for participants.

Who should consider this trial

Good fit: Ideal candidates include Latinx male couples who have been in a primary sexual relationship for at least three months and have reported unprotected anal sex.

Not a fit: Patients experiencing severe intimate partner violence or cognitive impairments that hinder informed consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce HIV transmission rates among Latino male couples.

How similar studies have performed: Previous studies targeting sexual minority Latinx men have shown promise, indicating potential for success with this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* at least 18 years
* reside in the 50 local jurisdictions identified by the EHE initiative or 17 jurisdictions with most HIV diagnoses among Latinxs
* identify as Latinx/Hispanic/Afro-Latinx or reports having a main partner who identifies as Latinx/Hispanic/Afro-Latin
* report having a main/primary male partner operationalized as a man with whom he has a primary ongoing sexual relationship, for at least 3 months
* at least one member of the dyad report three acts of unprotected of anal sex (with main or other partners)
* able to speak English and/or Spanish

Exclusion Criteria:

Either partner:

* reports severe intimate partner violence (IPV) within the dyad during the past year on the Revised Conflict Tactic Scale\[1-4\]
* has a language or cognitive impairment that would prevent informed consent. Inclusion of dyads reporting severe IPV could pose dangers and ethical concerns and will be referred to domestic abuse organizations for screening and services.
* adults unable to consent
* pregnant women
* prisoners
* individuals who are not yet adults

Where this trial is running

Orlando, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HIVLatinomalecouples
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.