Hip osteoarthritis: follow-up of patients treated with intra-articular hyaluronic acid

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects real-world data from adults aged 40 and older with hip osteoarthritis treated with intra-articular hyaluronic acid in several Spanish hospitals. Participants must have had symptoms for at least a year, radiographic KOA grades II–III, and a WOMAC score above 15, among other criteria. The investigation aims to document outcomes in standard clinical use rather than test an intervention. Data are drawn from patients treated within Traumatology and Rehabilitation departments of participating centers. The study is sponsored by Meiji Pharma Spain S.A. with academic and hospital collaborators.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: \>40 years at the time of study inclusion
* Preserved gait capability, with or without assistive devices
* Symptomatic hip arthropathy with a disease evolution of at least 1 year.
* Radiographic Kellgren-Lawrence grade II-III documented within the 12 months prior to study entry
* Total Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score \>15
* Patient currently receiving intra-articular hyaluronic acid treatment within 3 months prior to study inclusion

Exclusion Criteria:

* Refusal to provide written informed consent
* Females who are pregnant, breastfeeding, or not using effective contraception
* Body Mass Index (BMI) ≥ 30 kg/m²
* Presence of other chronic or autoimmune diseases that could interfere with clinical evaluation
* History of hypersensitivity or allergy to hyaluronic acid or its derivatives
* Prior administration of intra-articular platelet-rich plasma (PRP) or intra-articular corticosteroids within 3 months, or intra-articular hyaluronic acid within 6 months prior to study entry

Where it's running

• Hospital Universitario de La Princesa
  Madrid, Spain Recruiting
• Hospital Universitario de La Princesa
  Madrid, Spain Recruiting
• QuironSalud. Hospital Juan Bravo
  Madrid, Spain Recruiting
• Hospital Provincial Nuestra Señora de Gracia
  Zaragoza, Spain Not yet recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.