PENG nerve block with or without pulsed radiofrequency for chronic hip osteoarthritis pain

Evaluation of the Clinical Effectiveness of Pericapsular Nerve Group (PENG) Block and Pulsed Radiofrequency Applications in Chronic Hip Pain

Observational Ankara City Hospital Bilkent · NCT07360093

The study will try adding pulsed radiofrequency to a PENG nerve block to see if it reduces pain for longer in people with chronic hip osteoarthritis who still have significant pain despite conservative treatment.

Quick facts

Study typeObservational
Enrollment84 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorAnkara City Hospital Bilkent Academic / other
Locations1 site (Ankara)
Trial IDNCT07360093 on ClinicalTrials.gov

What this trial studies

This is a prospective observational comparison of two interventional approaches for chronic hip osteoarthritis pain: ultrasound-guided pericapsular nerve group (PENG) block alone versus PENG block combined with pulsed radiofrequency (PRF). The primary outcome is change in pain intensity measured by the Visual Analog Scale, and secondary outcomes include hip function assessed with validated functional scales. Eligible patients are adults with chronic hip pain lasting at least three months, baseline VAS ≥4, and inadequate response to conservative care. Procedures are performed at a single center with follow-up to determine whether adding PRF yields longer-lasting analgesia and functional benefit.

Who should consider this trial

Good fit: Adults with chronic hip pain for at least three months due to clinical or radiographic hip osteoarthritis, baseline VAS score of 4 or higher, and inadequate response to conservative treatments are ideal candidates.

Not a fit: Patients with hip pain from malignancy, prior hip arthroplasty, active local or systemic infection, uncorrectable coagulopathy or inability to stop anticoagulants, severe neurological deficit, or who are pregnant or breastfeeding are unlikely to benefit or are excluded.

Why it matters

Potential benefit: If successful, adding PRF to the PENG block could provide longer-lasting pain relief and better hip function, reducing the need for repeat procedures and improving daily activities.

How similar studies have performed: Previous small studies show PENG blocks provide short-term pain relief and PRF has produced promising results in other joint pain settings, but combining PENG with PRF has limited published data and remains relatively untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Presence of chronic hip pain lasting at least 3 months
* Baseline Visual Analog Scale (VAS) score ≥ 4
* Clinical and/or radiological diagnosis of hip osteoarthritis
* Inadequate response to conservative treatments

Exclusion Criteria:

* Local or systemic infection at the intervention site
* Coagulopathy or inability to discontinue anticoagulant therapy
* Hip pain related to malignancy
* History of previous hip arthroplasty
* Severe neurological deficit
* Pregnancy or breastfeeding

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Osteoarthritis of the HipOsteoarthritis, Hip,Pain, ChronicNerve BlockadePulsed Radiofrequency Treatment
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.