Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Hip muscle strengthening for chronic ankle instability in athletes

Official title: Comparison of the Effects of Hip and Ankle Focused Progressive Exercise Training on Lower Extremity Function in Athletes With Chronic Ankle Instability

Run by Hacettepe University · NCT07319403 · Data updated 2026-11-12

This study tests whether strengthening the hip muscles (gluteus medius vs. gluteus maximus) helps improve ankle stability and function in professional athletes with chronic ankle instability.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment36 (estimated)
SponsorHacettepe University
Academic / other
Locations1 site (Ankara, Çankaya)
StatusRecruiting
StartedFebruary 15, 2026
Main results expectedNovember 2026
Study endsNovember 2026
Registry record updatedOctober 13, 2026
Trial IDNCT07319403 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are professional athletes aged 18–40 with a history of lateral ankle sprains and repeated ankle instability.

Probably not a fit

Individuals without chronic ankle instability or those unable to participate in a structured strengthening program may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In athletes with chronic ankle instability, the study compares three groups: gluteus medius strengthening, gluteus maximus strengthening, and standard balance training. Participants are randomly assigned and undergo a structured, progressively loaded exercise program with supervised sessions. Baseline assessments are followed by a multi-week intervention and a post-intervention evaluation to measure functional and neuromuscular outcomes. The aim is to see if targeting specific hip muscles can improve lower-extremity stability and movement quality.

Why it matters

Potential benefit: If successful, participants may experience improved ankle stability and athletic performance through targeted hip strengthening.

How similar studies have gone: Previous research suggests proximal hip function can influence ankle stability, but results vary and this specific comparison is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Professional athletes aged between 18 and 40 years

Participation in sports for at least 3 years

History of at least one lateral ankle sprain that occurred at least 12 months prior to enrollment

At least two episodes of perceived ankle "giving way" and/or at least two recurrent lateral ankle sprains within the past 6 months, and/or a subjective feeling of ankle instability on the injured side

Exclusion Criteria:

History of lower extremity surgery

History of fracture involving the lower extremity

Any lower extremity injury within the past 3 months that limited physical activity for more than one day

Where it's running

  • Hacettepe University
    Ankara, Çankaya, Turkey (Türkiye)
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.