Clinical trial Recruiting at 1 site Observational Ages 18 to 60

Comparing two surgical methods for chronic ankle instability

Official title: The Clinical Outcomes Comparing the Modified Broström vs Anatomic Reconstruction Operation in Chronic Lateral Ankle Instability and Generalized Joint Laxity

Run by Peking University Third Hospital · NCT05196906 · Data updated 2026-11-12

This study is testing which of two surgical methods works better for people with chronic ankle instability to help them recover and feel better.

Quick facts

Study typeObservational
Ages18 Years to 60 Years
SexAll
Enrollment100 (estimated)
SponsorPeking University Third Hospital
Academic / other
Locations1 site (Beijing)
StatusRecruiting
StartedJanuary 1, 2020
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedApril 11, 2025
Trial IDNCT05196906 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 18 to 60 with a clinical diagnosis of lateral ankle pain and instability and a Beighton score of 4 or higher.

Probably not a fit

Patients with acute or subacute ankle injuries, significant lower extremity alignment issues, or advanced osteoarthritis may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare the clinical outcomes of the modified Broström operation and anatomical reconstruction for treating chronic lateral ankle instability (CLAI) and generalized joint laxity (GJL). It is a prospective cohort study that will assess primary outcomes using the Karlsson, Foot and Ankle Outcome Score (FAOS), and Foot and Ankle Ability Measure (FAAM) scores. Secondary outcomes include measuring anterior displacement and talar tilt angle in stress radiography, as well as the rate of re-injury. The goal is to determine which surgical method yields better results for patients with these conditions.

Why it matters

Potential benefit: If successful, this study could help identify the more effective surgical approach for patients suffering from chronic ankle instability and generalized joint laxity.

How similar studies have gone: While the modified Broström operation is commonly used, the comparative effectiveness of these two surgical methods in this specific patient population has not been extensively studied, making this a novel investigation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Clinical diagnosis of lateral ankle pain and instability Beighton score ≥4 Age with 18 to 60 years

Exclusion Criteria:

Patients with an acute or subacute ankle injury (within 3 months) Injury of the deltoid ligament Alignment of lower extremity greater than 5 degrees Fractures of the lower extremity Stage III or IV osteoarthritis Patients who refused to participate in the study

Where it's running

  • Peking University Third Hospital
    Beijing, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.