Comparing different surgical methods for chronic ankle instability

Comparison of Modified Broström Repair + Suture Tape and Anatomic Reconstruction for CLAI in Chronic Lateral Ankle Instability in Generalized Joint Laxity Cases: A Prospective Cohort Study

Peking University Third Hospital · NCT05698446

This study tests which of three different surgical methods works best for people with chronic ankle instability and loose joints to help them feel stronger and more stable.

Quick facts

Study typeObservational
Enrollment114 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorPeking University Third Hospital (other)
Locations1 site (Beijing)
Trial IDNCT05698446 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of three surgical approaches for treating chronic lateral ankle instability (CLAI) in patients with generalized joint laxity (GJL). It compares the modified Broström repair with suture tape augmentation, the modified Broström procedure alone, and an anatomic reconstruction. The goal is to determine which method provides better strength and stability while minimizing complications such as suture tape rejection or trauma from reconstruction. The study will involve a cohort of patients aged 18 to 60 who meet specific inclusion criteria.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 18 to 60 with a clinical diagnosis of lateral ankle pain and instability and a Beighton score of 4 or higher.

Not a fit: Patients with acute ankle injuries, significant lower extremity alignment issues, or advanced osteoarthritis may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced recurrence of instability for patients with chronic ankle instability.

How similar studies have performed: While there is existing research on surgical methods for ankle instability, this specific comparison of techniques with a focus on generalized joint laxity is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of lateral ankle pain and instability Beighton score ≥4 Age with 18 to 60 years

Exclusion Criteria:

* Patients with an acute or subacute ankle injury (within 3 months) Injury of the deltoid ligament Alignment of lower extremity greater than 5 degrees Fractures of the lower extremity Stage III or IV osteoarthritis Patients who refused to participate in the study

Where this trial is running

Beijing

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Ankle Sprains, Hypermobility Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.