High-Power Laser Therapy for Notalgia Paresthetica

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, assessor-blinded trial evaluates high-power laser therapy as an adjunct to standard care for notalgia paresthetica. Eligible adults with unilateral symptoms for at least 3 months and a minimum pruritus score will receive either active high-power laser treatment or sham laser, alongside their usual care. The study aims to measure changes in itching, pain, and quality of life over the treatment period. Outcomes will help determine if HPLT provides meaningful relief beyond standard therapies. The design addresses a gap in evidence for non-invasive options in this chronic neuropathic condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18-75 years
* Clinical diagnosis of unilateral Notalgia Paresthetica for at least 3 months
* Presence of characteristic symptoms (pruritus, paresthesia, and/or burning pain) in the typical T2-T6 dermatomal distribution
* A minimum score of 4 on the Numeric Rating Scale (NRS) for pruritus intensity
* Presence of hyperpigmentation in the affected area

Exclusion Criteria:

* \- Secondary causes of symptoms (e.g., spinal pathology, herpes zoster, renal failure)
* Previous spinal surgery in the thoracic region
* Coagulopathy or use of anticoagulant medication
* Skin diseases or infections in the treatment area
* Pregnancy or lactation
* Cognitive impairment affecting ability to complete questionnaires
* Previous treatment with botulinum toxin in the affected area within 6 months

Where it's running

• Usak University
  Uşak, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Ali Y Karahan, Prof.
• Email: ali.karahan@usak.edu.tr
• Phone: +905386921934

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.