High-Intensity Interval Training vs Moderate-Intensity Continuous Training for Chronic Non-Specific Low Back Pain
Official title: Comparison of High-Intensity Interval Training With Moderate-Intensity Connuous Training In Chronic Non-Specific Low Back Pain Patients: Randomized Clinical Trial
Run by Dow University of Health Sciences · NCT07645859 · Data updated 2026-11-12
This study tests whether a high-intensity interval training program helps reduce pain and improve function more than a moderate, steady-paced program in adults with chronic, non-specific low back pain.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 48 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Dow University of Health Sciences Academic / other |
| Locations | 1 site (Karachi) |
| Status | Recruiting |
| Started | May 14, 2026 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | June 12, 2026 |
| Trial ID | NCT07645859 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 20-48 with chronic (greater than 12 weeks) non-specific low back pain, mild to moderate pain (NPRS 3–5), and mild to moderate disability.
✕Probably not a fit
Individuals with specific spinal pathology, cardiopulmonary contraindications, pregnancy, recent surgery, or other exclusion criteria may not benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Participants with chronic non-specific low back pain are randomized to 6 weeks of either high-intensity interval training or moderate-intensity continuous training, with sessions monitored throughout. The study aims to compare impact on pain, disability, and quality of life, and to explore how baseline characteristics relate to outcomes. Interventions involve brisk walking and jogging as feasible, with adjustments for safety. Assessments occur before and after the program to measure changes in symptoms and function.
Why it matters
Potential benefit: If successful, the approach with HIIT could offer a more effective or time-efficient option to reduce pain and improve daily functioning for people with chronic non-specific low back pain.
How similar studies have gone: Prior research has shown variable results; this trial explores whether HIIT offers advantages over traditional aerobic training in this condition.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Referred patients of back pain persisting for \> 12 weeks with no identifiable specific cause or underlying pathology from DUH OPD who meet the eligibility criteria. * Age group 20-48 with either gender. * NPRS score ranging between 3 and 5 (mild to moderate). * Modified ODI score is mild to moderate. Exclusion Criteria: * Any client with a specific cause of LBP (neurological problems, fractures, malignancy, infections, or rheumatic diseases such as RA or ankylosing spondylitis). * Any client with cardiopulmonary problems (recent myocardial infarction, uncontrolled hypertension, asthma, COPD). * Any client with musculoskeletal disorders \[injuries limiting exercises, spine injuries, recent trauma (fracture), scoliosis by Forward Adam's test\]. * Any client with metabolic conditions (thyroid problems, uncontrolled diabetes). * Pregnancy / first 3-6 months postpartum. * Recent surgery.
Where it's running
-
Dr. Ariba Sohail (PT)
Karachi, Pakistan Recruiting
Study contacts
- Principal investigator: Ariba Sohail — Dow University of Health Sciences
- Study coordinator: Ariba Dr. Ariba Sohail (PT)
- Email: aribasohail123@gmail.com
- Phone: +923480218683
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Exercise effect on the lumbar multifidus in back pain
This study tests whether a 12-week home rehab program can change ultrasound features of the lumbar multifidus and reduce pain in adults with chronic non-specific low back pain from multifidus injury.
-
McGill Stabilization Exercises vs Sahrmann Movement-Based Exercises for Chronic Low Back Pain
This trial tests whether McGill stabilization exercises or Sahrmann's movement-based exercises better reduce pain and improve motion and function in adults with chronic non-specific low back pain.
-
Whole-body vibration vs. Pilates for chronic low back pain in young adults
This trial tests whether whole-body vibration or Pilates, each with standard physiotherapy, better reduces pain and improves balance and function in adults with chronic non-specific low back pain.
-
Isokinetic Profile of Ankle Muscles in Chronic Non-Specific Low Back Pain Patients
This study tests how ankle muscle performance differs in men with chronic non-specific low back pain compared with typical expectations, using isokinetic testing to explore links between pain, function, and fatigue.
-
VR-MBCT for chronic nonspecific low back pain
A multi-center trial will test whether adding virtual reality-based mindfulness therapy to usual care helps adults with chronic nonspecific low back pain feel better and move more in 8 weeks.
-
Does adding Myofascial Release to Clinical Pilates help chronic low back pain more than Pilates alone?
This study tests whether adding Myofascial Release Technique to a 6-week Clinical Pilates program reduces pain and improves function in adults with chronic non-specific low back pain.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.