High intensity interval training for lung cancer patients after surgery

Comparison of the Effects of Continuous Aerobic Exercise Training and Low Volume High Intensity Interval Training on Cardiopulmonary Exercise Capacity, Autonomic Function and Oxidative Stress in Operated Lung Cancer Patients

Not applicable Interventional Hacettepe University · NCT05837429

This study tests if a special exercise program can help lung cancer patients recover better after their surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorHacettepe University Academic / other
Drugs / interventionschemotherapy
Locations1 site (Ankara, Sıhhiye)
Trial IDNCT05837429 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of low volume high intensity interval training on patients who have undergone surgery for non-small cell lung cancer. Participants will be randomly assigned to two groups, each receiving different exercise protocols on a bicycle ergometer under physiotherapist supervision. The training consists of a warm-up, high-intensity intervals, and a cool-down phase, with the intensity tailored to each patient's maximal oxygen consumption. The study aims to assess the impact of this exercise regimen on patients' recovery and overall health post-surgery.

Who should consider this trial

Good fit: Ideal candidates are patients diagnosed with non-small cell lung cancer, stage 3A or earlier, who have completed adjuvant treatments and are clinically stable in remission.

Not a fit: Patients who have undergone pneumonectomy surgery or have advanced COPD, cardiac disease, or orthopedic/neurological issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance recovery and improve the quality of life for lung cancer patients after surgery.

How similar studies have performed: Other studies have shown positive outcomes with high intensity interval training in cancer recovery, suggesting this approach may be beneficial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed with Non-Small Cell Lung Cancer
* Stage 3A and earlier
* Operated and at least 6 months have expired since the surgery
* Having completed adjuvant treatments such as chemotherapy and radiotherapy and at least 6 months have expired
* Being clinically stable and in remission
* Not having new recurrence and active cancer

Exclusion Criteria:

* Pneumonectomy surgery
* Presence of symptoms, signs and diagnoses indicating the presence of lung and cardiac disease such as advanced COPD
* Having any orthopedic or neurological problem that may prevent exercise
* Presence of recurrence or active cancer

Where this trial is running

Ankara, Sıhhiye

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung CancerNon Small Cell Lung CancerLow volume high intensity interval trainingAerobic exerciseOxidative stressCardiopulmonary exercise test
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.