High intensity eHealth program to help childhood cancer survivors with learning disparities
Leveraging Digital Health Solutions to Reduce Learning and Functional Disparities in Children With Cancer
NA · City of Hope Medical Center · NCT05428176
This study tests whether a special online program can help children who survived leukemia or lymphoma improve their learning and school performance compared to those who only get regular care.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 332 (estimated) |
| Ages | 6 Years and up |
| Sex | All |
| Sponsor | City of Hope Medical Center (other) |
| Locations | 4 sites (Duarte, California and 3 other locations) |
| Trial ID | NCT05428176 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates a high intensity electronic health intervention aimed at reducing learning disparities in children who are survivors of acute leukemia and lymphoblastic lymphoma. The program involves providing parents with educational resources and parenting tips through videoconferencing and a dedicated website. Participants are randomized into two groups: one receiving the eHealth intervention alongside usual care, and the other receiving only usual care. The effectiveness of this intervention on children's learning and school-related outcomes will be assessed over a 12-month period.
Who should consider this trial
Good fit: Ideal candidates are children aged 6-12 years who have completed treatment for acute leukemia or lymphoblastic lymphoma and are currently in remission.
Not a fit: Patients with severe neurodevelopmental disorders or those currently participating in similar behavioral intervention studies may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve academic performance and learning outcomes for childhood cancer survivors.
How similar studies have performed: While there have been studies focusing on educational interventions for cancer survivors, this specific high intensity eHealth approach is relatively novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Documented informed consent of the participant and/or legally authorized representative * Assent, when appropriate, will be obtained per institutional guidelines * Primary participating parent/caregiver is English- or Spanish-speaking (any race/ethnicity) * Child is aged 6-12 years (yr.) (for the website usability pre-study, child is age 8 - 12 yrs.) * Child understands English (but can be bilingual) * Child treated for acute leukemia (e.g., acute lymphoblastic leukemia, acute myelogenous leukemia) or lymphoblastic lymphoma * Child is in cancer remission and has completed cancer therapies, including maintenance treatment * Primary participating parent/caregiver has daily contact with the child * Child is enrolled in school Exclusion Criteria: * Recent or current participation in a behavioral intervention study with a similar focus * History of major psychiatric condition (e.g., psychosis) in parent or child * Severe neurodevelopmental disorder in the child (e.g., down syndrome, intellectual disability) * Child has previously used the IXL online learning program extensively and unwilling to regularly use it again * Any other condition that would, in the investigator's judgment, contraindicate the patient's participation in the clinical study due to safety concerns with clinical study procedures * Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics)
Where this trial is running
Duarte, California and 3 other locations
- City of Hope Medical Center — Duarte, California, United States (RECRUITING)
- Childrens Hospital of Los Angeles — Los Angeles, California, United States (RECRUITING)
- Rady Children's Hospital San Diego — San Diego, California, United States (RECRUITING)
- University of Calif San Francisco — San Francisco, California, United States (RECRUITING)
Study contacts
- Principal investigator: Sunita K Patel — City of Hope Medical Center
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Lymphoblastic Lymphoma