Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparing latex and non-latex bands for treating hemorrhoids

Official title: Single-blinded Randomized Trial of Latex vs Non-latex Hemorrhoid Banding

Run by Huntington Memorial Hospital · NCT06625138 · Data updated 2026-11-12

This study is testing whether non-latex bands work as well as latex bands for treating hemorrhoids in adults and looking at any side effects they might cause.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment164 (estimated)
SponsorHuntington Memorial Hospital
Academic / other
Locations1 site (Pasadena, California)
StatusRecruiting
StartedAugust 30, 2024
Main results expectedDecember 1, 2026
Study endsDecember 1, 2026
Registry record updatedSeptember 17, 2026
Trial IDNCT06625138 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults with symptomatic grade 2-3 internal hemorrhoids who require rubber band ligation.

Probably not a fit

Patients with known latex allergies, recent hemorrhoidal banding, or certain medical conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study recruits adult patients with symptomatic grade 2-3 internal hemorrhoids who are candidates for rubber band ligation. Participants will be randomly assigned to receive either a latex band or a non-latex band for treatment. The primary goal is to evaluate the effectiveness of non-latex bands compared to latex bands, while also assessing any associated adverse effects such as pain and bleeding within three weeks post-treatment.

Why it matters

Potential benefit: If successful, this study could provide a safer alternative for patients with latex allergies undergoing hemorrhoid treatment.

How similar studies have gone: While the approach of comparing latex and non-latex bands is not widely tested, similar studies in other areas of medical treatment have shown promising results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Symptomatic grade 2-3 internal hemorrhoids undergoing rubber band ligation

Exclusion Criteria:

* Previous hemorrhoidal banding within the past year
* Known latex allergy
* Pregnancy
* Anticoagulation use
* Bleeding disorder
* Portal hypertension
* Inflammatory bowel disease
* Immunosuppression
* Functional neurologic disorder
* Pelvic floor dysfunction
* Any records flagged "break the glass" or "research opt out".

Where it's running

  • Huntington Memorial Hospital
    Pasadena, California, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.