Comparing latex and non-latex bands for treating hemorrhoids
Official title: Single-blinded Randomized Trial of Latex vs Non-latex Hemorrhoid Banding
Run by Huntington Memorial Hospital · NCT06625138 · Data updated 2026-11-12
This study is testing whether non-latex bands work as well as latex bands for treating hemorrhoids in adults and looking at any side effects they might cause.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 164 (estimated) |
| Sponsor | Huntington Memorial Hospital Academic / other |
| Locations | 1 site (Pasadena, California) |
| Status | Recruiting |
| Started | August 30, 2024 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | September 17, 2026 |
| Trial ID | NCT06625138 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with symptomatic grade 2-3 internal hemorrhoids who require rubber band ligation.
✕Probably not a fit
Patients with known latex allergies, recent hemorrhoidal banding, or certain medical conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study recruits adult patients with symptomatic grade 2-3 internal hemorrhoids who are candidates for rubber band ligation. Participants will be randomly assigned to receive either a latex band or a non-latex band for treatment. The primary goal is to evaluate the effectiveness of non-latex bands compared to latex bands, while also assessing any associated adverse effects such as pain and bleeding within three weeks post-treatment.
Why it matters
Potential benefit: If successful, this study could provide a safer alternative for patients with latex allergies undergoing hemorrhoid treatment.
How similar studies have gone: While the approach of comparing latex and non-latex bands is not widely tested, similar studies in other areas of medical treatment have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Symptomatic grade 2-3 internal hemorrhoids undergoing rubber band ligation Exclusion Criteria: * Previous hemorrhoidal banding within the past year * Known latex allergy * Pregnancy * Anticoagulation use * Bleeding disorder * Portal hypertension * Inflammatory bowel disease * Immunosuppression * Functional neurologic disorder * Pelvic floor dysfunction * Any records flagged "break the glass" or "research opt out".
Where it's running
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Huntington Memorial Hospital
Pasadena, California, United States Recruiting
Study contacts
- Principal investigator: Adam Truong, MD — Huntington Health
- Study coordinator: Adam Truong, MD
- Email: adam.truong@huntingtonhealth.org
- Phone: (626) 397-5896
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Hemorrhoid Artery Embolization (HAE) for Bleeding Internal Hemorrhoids: A Real-World Registry
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.