Comparing latex and non-latex bands for treating hemorrhoids
Single-blinded Randomized Trial of Latex Vs Non-latex Hemorrhoid Banding
This study is testing whether non-latex bands work as well as latex bands for treating hemorrhoids in adults and looking at any side effects they might cause.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 164 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Huntington Memorial Hospital Academic / other |
| Locations | 1 site (Pasadena, California) |
| Trial ID | NCT06625138 on ClinicalTrials.gov |
What this trial studies
This study recruits adult patients with symptomatic grade 2-3 internal hemorrhoids who are candidates for rubber band ligation. Participants will be randomly assigned to receive either a latex band or a non-latex band for treatment. The primary goal is to evaluate the effectiveness of non-latex bands compared to latex bands, while also assessing any associated adverse effects such as pain and bleeding within three weeks post-treatment.
Who should consider this trial
Good fit: Ideal candidates are adults with symptomatic grade 2-3 internal hemorrhoids who require rubber band ligation.
Not a fit: Patients with known latex allergies, recent hemorrhoidal banding, or certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a safer alternative for patients with latex allergies undergoing hemorrhoid treatment.
How similar studies have performed: While the approach of comparing latex and non-latex bands is not widely tested, similar studies in other areas of medical treatment have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Symptomatic grade 2-3 internal hemorrhoids undergoing rubber band ligation Exclusion Criteria: * Previous hemorrhoidal banding within the past year * Known latex allergy * Pregnancy * Anticoagulation use * Bleeding disorder * Portal hypertension * Inflammatory bowel disease * Immunosuppression * Functional neurologic disorder * Pelvic floor dysfunction * Any records flagged "break the glass" or "research opt out".
Where this trial is running
Pasadena, California
- Huntington Memorial Hospital — Pasadena, California, United States (Recruiting)
Study contacts
- Principal investigator: Adam Truong, MD — Huntington Health
- Study coordinator: Adam Truong, MD
- Email: adam.truong@huntingtonhealth.org
- Phone: (626) 397-5896
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.