Heart Rate Variability, Music, and Preprocedure Mood

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this prospective cohort pilot, researchers will examine how heart rate variability relates to anxiety and depression in patients listening to music before procedures. The study will enroll about 120 adults across three Singapore hospitals and record ECG before, during, and after music listening, alongside preprocedural demographic and psychological information. By comparing HRV metrics with anxiety and depression scores, the team aims to understand if music can modulate autonomic balance and mood in the perioperative setting. ECG monitoring and music listening are the two interventions used. The work builds on prior data suggesting music can reduce perioperative anxiety and may influence inflammatory responses, offering a potentially safe, low-cost approach to improve patient experience.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. America Society of Anaesthesiologist (ASA) 1 to 3 adults undergoing procedures (surgery, pain procedures);
2. Able to read and understand English and/or Chinese;
3. Not receiving opioid prior to the procedures.

Exclusion Criteria:

1. With chronic pain;
2. Opioid and drug abuse;
3. Scheduled postoperative Intensive care unit (ICU) admission;
4. With baseline non-sinus heart rhythm or on pacemaker support.

Where it's running

• KK Women's and Children's Hospital
  Singapore, Singapore Recruiting
• Changi General Hospital
  Singapore, Singapore Not yet recruiting
• Singapore General Hospital
  Singapore, Singapore Not yet recruiting

Study contacts

• Principal investigator: Ban Leong Sng — KK Women's and Children's Hospital
• Study coordinator: Ban Leong Sng
• Email: sng.ban.leong@singhealth.com.sg
• Phone: 65 6394 8436

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.