Healthy aging education for people with epilepsy who are 55 and older
Official title: Healthy Aging in People With Epilepsy Program (HAP-E): Closing the Gap in Epilepsy Care
Run by The Cleveland Clinic · NCT06052605 · Data updated 2026-11-12
This trial tests whether a 12-week educational program about healthy aging, dementia risk factors, and chronic disease management can improve dementia knowledge and quality of life for older adults with epilepsy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 55 Years to 90 Years |
| Sex | All |
| Enrollment | 380 (estimated) |
| Sponsor | The Cleveland Clinic Academic / other |
| Locations | 1 site (Cleveland, Ohio) |
| Status | Recruiting |
| Started | March 25, 2026 |
| Main results expected | July 31, 2030 |
| Study ends | August 1, 2030 |
| Registry record updated | June 12, 2026 |
| Trial ID | NCT06052605 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 55 or older with a neurologist-confirmed diagnosis of epilepsy, English-speaking, able to participate in a 12-week program.
✕Probably not a fit
Individuals aged 90 or older or those with dementia at screening may receive little or no direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study will randomize adults aged 55 and older with epilepsy to an education program or a control condition. The 12-week group program covers healthy aging, dementia risk factors, and lifestyle strategies, with pre- and post-program assessments for all participants. The study also collects surveys from healthcare providers involved in epilepsy care. Outcomes focus on dementia knowledge, health literacy, and quality of life, with analyses comparing intervention and control groups. The trial is led by Anny Reyes with NINDS collaboration at Cleveland Clinic.
Why it matters
Potential benefit: If successful, participants may gain better understanding of dementia risk and improved quality of life through healthier aging practices.
How similar studies have gone: Prior educational interventions in aging and epilepsy have shown improvements in health literacy and quality of life in some cohorts, though this exact program is novel for this population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Part 1a - Patient Survey: * Current diagnosis of epilepsy made by a neurologist, epileptologist, or internist/family medicine physician * Age 55 years or older * Proficiency in English (self-assessed) * Part 1b - Provider Survey: * Healthcare professional in the US who is involved in the clinical care or treatment of individuals with epilepsy (including Epilepsy Foundation organizational leaders) * Part 3: * Current diagnosis of epilepsy made by a neurologist, epileptologist, or internist/family medicine physician * Age 55 years or older (up to 90) * Proficiency in English (self-assessed) Exclusion Criteria: * Part 1a: * Evidence of Dementia (based on phone cognitive screener; those with suspected mild cognitive impairment will not be excluded) * Age 90 years or older * Part 3: * Evidence of Dementia (based on phone cognitive screener; those with suspected mild cognitive impairment will not be excluded) * Age 90 years or older
Where it's running
-
Cleveland Clinic
Cleveland, Ohio, United States Recruiting
Study contacts
- Principal investigator: Anny Reyes, PhD — The Cleveland Clinic
- Study coordinator: Anny Reyes, PhD
- Email: REYESA14@ccf.org
- Phone: 216-390-4266
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.