Health and Wellness Coaching to Support Adherence in Papillary and Follicular Thyroid Cancer Survivors
Official title: Health and Wellness Coaching to Improve Patient Activation and Adherence to Healthy Habits in Differentiated Thyroid Cancer Care: A Mixed-Methods Pilot Study
Run by Mayo Clinic · NCT07545837 · Data updated 2026-11-12
This study tests whether a patient-centered health and wellness coaching program helps adults with papillary or follicular thyroid cancer stick to treatment plans and healthy habits.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Jacksonville, Florida) |
| Status | Recruiting |
| Started | June 23, 2026 |
| Main results expected | June 30, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | July 8, 2026 |
| Trial ID | NCT07545837 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with histologically confirmed papillary or follicular thyroid carcinoma who have had total thyroidectomy ± radioactive iodine and are on levothyroxine mono-therapy with TSH < 4 uIU/mL for at least 3 months.
✕Probably not a fit
Patients who are not English-speaking, have cognitive/psychiatric impairment, or are receiving active systemic cancer therapy may not benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional effort pairs counseling, interviews, and questionnaires to encourage adherence to thyroid cancer treatment and healthy lifestyle practices in adults who have undergone total thyroidectomy and are on levothyroxine. The program aims to address fatigue, mood changes, and daily-life disruptions that can affect self-care and treatment adherence. Eligible participants are adults with papillary or follicular thyroid carcinoma who meet specific thyroid and treatment criteria and can provide consent in English. The study is conducted at Mayo Clinic in Florida and is led by Mayo Clinic with no listed collaborators. Outcomes will inform whether health and wellness coaching can improve long-term management in this population.
Why it matters
Potential benefit: If successful, participants may experience improved adherence to treatment and healthier lifestyle habits, potentially enhancing quality of life and disease management.
How similar studies have gone: Prior work suggests health coaching can promote behavior change in various cancer survivorship populations, but application to thyroid cancer cohorts is not well established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults ≥ 18 years * Histologically confirmed papillary or follicular thyroid carcinoma * Status post total thyroidectomy ± radioactive iodine therapy * Receiving levothyroxine monotherapy (no triiodothyronine \[T3\] or desiccated thyroid products) * Thyroid-stimulating hormone (TSH) \< 4 uIU/mL at ≥ 3 months post-thyroidectomy * English proficiency * Ability to provide informed consent Exclusion Criteria: * Medullary or anaplastic thyroid carcinoma * Current systemic therapy for thyroid or other cancers * Cognitive or psychiatric impairment precluding participation * Inability to complete study procedures
Where it's running
-
Mayo Clinic in Florida
Jacksonville, Florida, United States Recruiting
Study contacts
- Principal investigator: Abd Moain Abu Dabrh, MB, BCh, MS — Mayo Clinic
- Study coordinator: Clinical Trials Referral Office
- Email: mayocliniccancerstudies@mayo.edu
- Phone: 855-776-0015
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.