H. pylori and insulin resistance in people with metabolic syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This retrospective cohort review uses medical records from 100 patients with metabolic syndrome seen at the Center for New Medical Technologies in Novosibirsk. Patients are divided into two groups of 50 with and without confirmed H. pylori infection based on breath test, stool antigen, or biopsy results, and fasting labs and metabolic parameters were extracted. The primary endpoint is the difference in HOMA-IR between the infected and non-infected groups; secondary analyses examine correlations between infection persistence, markers of gastric inflammation (gastro panel, CRP), and other metabolic markers. Statistical comparisons and correlation analyses will determine whether persistent H. pylori infection is linked to greater insulin resistance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Verified MS per NCEP-ATP III criteria.
* Ability to undergo all procedures (fasting blood draw, breath test, stool antigen, endoscopy/biopsy, anthropometry).

Exclusion Criteria:

* Current metabolic-influencing therapy.
* Acute/chronic infection or autoimmune flare.
* Interventional study participation in last 3 months.
* Planned surgery/long hospitalization.
* Active malignancies.
* Severe liver/kidney failure.
* Pregnancy/lactation.
* Gastric resection or upper GI reconstruction.
* Type 1 diabetes.

Where it's running

• Center of New Medical Technologies
  Novosibirsk, Novosibirsk Oblast, Russia Recruiting

Study contacts

• Study coordinator: Evgeniya V Shrainer, PhD
• Email: shrayner_ev@cnmt.ru
• Phone: 983 300 22 05

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Fulvic acid supplements for metabolic syndrome

  This study tests whether 50 mg or 100 mg of fulvic acid daily for 12 weeks can help people with metabolic syndrome or prediabetes.

  Recruiting Arizona State University · Phoenix, Arizona · NCT07927283

• Asprosin and miRNA Profiles in Young Women with Metabolic Syndrome

  This study tests whether certain blood biomarkers, including asprosin and six microRNAs, differ between young women with metabolic syndrome and healthy peers.

  Recruiting University of Applied Sciences in Nowy Targ · Nowy Targ, Lesser Poland Voivodeship · NCT07917364

• Using Multimodal Ultrasound to Check Muscle Mass in Metabolic Disease Patients

  This study tests whether a multimodal ultrasound approach can accurately measure muscle mass in people with metabolic syndrome, obesity, sarcopenia, or type 2 diabetes.

  Recruiting Zhangzhou Municipal Hospital · Zhangzhou, Fujian · NCT07836088

• Low-Calorie Diet in adolescents with Familial Mediterranean Fever and metabolic syndrome

  A group of adolescents with both FMF and metabolic syndrome will try a low-calorie diet for 3 months to see if it helps manage metabolic symptoms.

  Recruiting Cairo University · Giza, Dokki · NCT07833007

• Exercise for Metabolic Syndrome and Fatty Liver in Adolescent Girls with Celiac Disease

  This study tests whether a 3-month walking program helps improve metabolic syndrome and fatty liver in adolescent females with celiac disease.

  Recruiting Cairo University · Giza, Dokki · NCT07832994

• Longevity Metrics AI/ML Development Study

  Researchers are testing AI models that score health screening tests and predict outcomes like life expectancy for adults, using ongoing follow-up data.

  Recruiting Longevity Metrics, Inc. · Boulder, Colorado · NCT07808619

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.