Group Unified Protocol for Emotional Disorders in adults in public mental health (UP in Spanish)

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial adapts the Spanish UP for group delivery in the Spanish Public Mental Health System to treat adults with emotional disorders. Participants are randomized to receive the UP in groups or treatment as usual, with outcomes assessed at baseline, after treatment, and at 3 months. The study measures anxiety, depression, somatic symptoms, functioning, quality of life, and participant satisfaction to determine effectiveness, feasibility, and acceptability in routine clinical practice. It also explores whether the approach could reduce demand on public mental health services.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18 to 65 years.
* Ability and willingness to provide written informed consent.
* Sufficient proficiency in Spanish to participate in the intervention and complete study assessments.
* Sufficient cognitive capacity to understand the intervention content.
* A primary diagnosis of an emotional disorder with mild, moderate, or severe symptom severity, including Depressive Disorders, Anxiety Disorders, Obsessive-Compulsive and Related Disorders, Trauma and Stressor-Related Disorders, Dissociative Disorders and Somatic Symptom and Related Disorders.
* Presence of emotional symptoms (e.g., anxiety, depressive, or phobic symptoms), somatic symptoms, obsessive symptoms, and/or avoidance behaviors associated with clinically significant impairment, as indicated by moderate or higher scores on the GAD-7, PHQ-9, and/or PHQ-15.

Exclusion Criteria:

* Refusal to provide informed consent or withdrawal of consent during the study.
* Current severe substance use disorder or behavioral addiction.
* Current high suicide risk.
* Current psychotic symptoms or psychotic disorder.
* Neurological disorders or severe medical conditions that could interfere with participation in or adherence to the intervention.
* Intellectual disability, significant language difficulties, or any other condition that may impair the participant's ability to understand the intervention content.

Where it's running

• Centro de Salud Espartero
  Logroño, La Rioja, Spain Recruiting

Study contacts

• Principal investigator: Patricia Fernández Couto, Clinical Psychologist — Servicio Riojano de Salud
• Study coordinator: Patricia Fernández-Couto, Clinical Psychologist
• Email: pafernco@unirioja.es
• Phone: (+34)941296251

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Digital stepped-care mindfulness program for emotional disorders

  This project tests whether adding an online mindfulness program to usual care helps adults (18–65) with depression, anxiety, OCD, or PTSD recover faster and stay well longer.

  Recruiting Peking University · Beijing · NCT07458100

• Understanding anxiety, depression, and bipolar disorder over time in China

  This study tests how anxiety, depressive, and bipolar symptoms change over three years to find patterns that help with earlier recognition and prediction in people aged 12–55.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT07903246

• Aerobic Exercise as an Adjunct Therapy for Depression

  This study tests whether adding a structured aerobic exercise program to standard antidepressant and therapy helps reduce depression severity more than standard care alone.

  Recruiting Combined Military Hospital Bahawalpur · Chak Eighty-seven -Twelve Left, Punjab Province · NCT07819448

• Metformin added to antidepressants for depression with obesity in Pakistani adults

  This study tests whether adding metformin to antidepressant therapy helps reduce depressive symptoms and BMI in adults with depression and overweight/obesity in Pakistan.

  Recruiting at 2 sites Riphah International University · Rawalpindi, Punjab Province and 1 other locations · NCT07654179

• Parent group program using the Unified Protocol for teens with autism and anxiety/depression

  This trial tests a parent-guided adaptation of the Unified Protocol to help adolescents with autism and co-occurring anxiety or depression.

  Recruiting Sahlgrenska University Hospital · Gothenburg · NCT07637799

• Mindfulness‑augmented brain stimulation for treatment‑resistant depression

  This trial will test whether combining fast brain stimulation (iTBS) with a digital mindfulness program helps people with treatment‑resistant depression reduce symptoms and improve thinking.

  Recruiting Phase 2 University of California, San Diego · San Diego, California · NCT07512284

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.