Registry for patients with left ventricular thrombus
Official title: Observational Registry to Determine the Predictors and Outcomes of Patients at Risk of and Diagnosed With Left Ventricular Thrombus
Run by Queen Mary University of London · NCT06963567 · Data updated 2026-11-12
This study is gathering information from people with blood clots in the heart to better understand the condition and improve treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1500 (estimated) |
| Sponsor | Queen Mary University of London Academic / other |
| Locations | 8 sites (Cambridge, Cambridgeshire and 7 other locations) |
| Status | Recruiting |
| Started | May 17, 2024 |
| Main results expected | January 31, 2027 |
| Study ends | January 31, 2027 |
| Registry record updated | July 16, 2026 |
| Trial ID | NCT06963567 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients diagnosed with left ventricular thrombus or those at high risk for developing it due to severe left ventricular dysfunction or a history of myocardial infarction.
✕Probably not a fit
Patients under 18 years of age or those unable to provide consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to gather data on patients with left ventricular thrombus (LVT), a condition where blood clots form in the heart's main chamber, often following a heart attack or in cases of heart failure. By collecting information on patient demographics, clinical factors, and quality of life, the study seeks to enhance understanding of LVT formation and management. Participants will have their blood and scan results recorded, and may complete a quality of life questionnaire during routine MRI scans. The ultimate goal is to improve treatment strategies for LVT and reduce associated complications such as stroke.
Why it matters
Potential benefit: If successful, this study could lead to improved management and treatment strategies for patients at risk of or suffering from left ventricular thrombus.
How similar studies have gone: While there may be existing studies on left ventricular thrombus, this registry approach is aimed at enhancing understanding and management, making it a valuable addition to the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with LV thrombus or; * Patients at risk for developing LV thrombus (e.g severe LV dysfunction, LV aneurysm, MI. Exclusion Criteria: * Age \< 18 years * Unable to consent
Where it's running
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Royal Papworth Hospital
Cambridge, Cambridgeshire, United Kingdom Recruiting -
Lancashire Cardiac Centre
Blackpool, United Kingdom Recruiting -
Leeds General Infirmary
Leeds, United Kingdom Recruiting -
St Bartholomew's Hospital
London, United Kingdom Recruiting -
Imperial College Healthcare London
London, United Kingdom Recruiting -
Basildon University Hospital
London, Essex, United Kingdom Not yet recruiting
Show 2 more locations
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James Cook University Hospital
Middlesbrough, North Yorkshire, United Kingdom Not yet recruiting -
Sunderland Royal Hospital
Sunderland, Tyne and Wear, United Kingdom Not yet recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Apixaban vs Warfarin for a Left Ventricular Thrombus
This study tests whether apixaban can more conveniently and safely dissolve a left ventricular blood clot compared with warfarin.
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Using Apixaban to prevent blood clots after heart attacks
This study is testing if a low dose of Apixaban can help prevent blood clots in people who have had a heart attack and have weak heart function.
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Apixaban versus warfarin for left ventricular clot after a heart attack
This compares apixaban and warfarin to see which better clears left-ventricular blood clots in adults after a heart attack.
-
Anticoagulation After a Heart Attack with Left Ventricular Clot
This study tests whether adding rivaroxaban to standard dual antiplatelet therapy helps people who develop a left ventricular thrombus after a STEMI.
-
Comparing anticoagulants for treating left ventricular thrombus after heart attacks in Nepal
This study is testing whether two blood-thinning medications, Rivaroxaban and Warfarin, can help people in Nepal with blood clots in the heart after a heart attack.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.