Clinical trial Recruiting at 5 sites Observational Ages 18 and up

Registry for patients with left ventricular thrombus

Official title: Observational Registry to Determine the Predictors and Outcomes of Patients at Risk of and Diagnosed With Left Ventricular Thrombus

Run by Queen Mary University of London · NCT06963567 · Data updated 2026-11-12

This study is gathering information from people with blood clots in the heart to better understand the condition and improve treatment options.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1500 (estimated)
SponsorQueen Mary University of London
Academic / other
Locations8 sites (Cambridge, Cambridgeshire and 7 other locations)
StatusRecruiting
StartedMay 17, 2024
Main results expectedJanuary 31, 2027
Study endsJanuary 31, 2027
Registry record updatedJuly 16, 2026
Trial IDNCT06963567 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients diagnosed with left ventricular thrombus or those at high risk for developing it due to severe left ventricular dysfunction or a history of myocardial infarction.

Probably not a fit

Patients under 18 years of age or those unable to provide consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather data on patients with left ventricular thrombus (LVT), a condition where blood clots form in the heart's main chamber, often following a heart attack or in cases of heart failure. By collecting information on patient demographics, clinical factors, and quality of life, the study seeks to enhance understanding of LVT formation and management. Participants will have their blood and scan results recorded, and may complete a quality of life questionnaire during routine MRI scans. The ultimate goal is to improve treatment strategies for LVT and reduce associated complications such as stroke.

Why it matters

Potential benefit: If successful, this study could lead to improved management and treatment strategies for patients at risk of or suffering from left ventricular thrombus.

How similar studies have gone: While there may be existing studies on left ventricular thrombus, this registry approach is aimed at enhancing understanding and management, making it a valuable addition to the field.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with LV thrombus or;
* Patients at risk for developing LV thrombus (e.g severe LV dysfunction, LV aneurysm, MI.

Exclusion Criteria:

* Age \< 18 years
* Unable to consent

Where it's running

  • Royal Papworth Hospital
    Cambridge, Cambridgeshire, United Kingdom
    Recruiting
  • Lancashire Cardiac Centre
    Blackpool, United Kingdom
    Recruiting
  • Leeds General Infirmary
    Leeds, United Kingdom
    Recruiting
  • St Bartholomew's Hospital
    London, United Kingdom
    Recruiting
  • Imperial College Healthcare London
    London, United Kingdom
    Recruiting
  • Basildon University Hospital
    London, Essex, United Kingdom
    Not yet recruiting
Show 2 more locations
  • James Cook University Hospital
    Middlesbrough, North Yorkshire, United Kingdom
    Not yet recruiting
  • Sunderland Royal Hospital
    Sunderland, Tyne and Wear, United Kingdom
    Not yet recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.