GNRI and PNI to predict short-term outcomes in older adults with multiple rib fractures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center, observational cohort study conducted in the Emergency Department at Ankara Etlik City Hospital. It will enroll adults aged 65 or older with isolated blunt thoracic trauma and more than three rib fractures, collecting routine clinical, laboratory, anthropometric, imaging, and follow-up data. The main goal is to see if GNRI and PNI can predict a composite short-term poor outcome, including death, ICU admission, ventilation, pneumonia, atelectasis, chest tube insertion, or hospital stay of seven days or more. Secondary analyses will look at the individual components of the composite outcome. No experimental interventions are used beyond standard care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 65 years or older.
2. Presentation to the emergency department with blunt thoracic trauma.
3. More than three rib fractures confirmed by thoracic computed tomography or another appropriate radiologic method.
4. Isolated thoracic trauma without major extra-thoracic injury.
5. Serum albumin level, total lymphocyte count, height, and weight available within the first 24 hours after presentation.
6. Written informed consent obtained from the patient or the legally authorized representative.

Exclusion Criteria:

1. Penetrating thoracic trauma.
2. Single rib fracture.
3. Intubation at presentation.
4. Polytrauma or major extra-thoracic injury.
5. Known advanced liver failure, nephrotic syndrome, end-stage renal disease, or hematologic disease that may substantially affect albumin or lymphocyte levels.
6. Active malignancy or cachexia related to advanced malignancy.
7. Missing data.
8. Refusal to participate in the study.

Where it's running

• Ankara Etlik City Hospital, Department of Emergency Medicine
  Ankara, Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Tuğba Sanalp Menekşe, MD
• Email: tugba.sanalp@hotmail.com
• Phone: +90 551 414 64 22

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.