Cryoablation for pain relief in rib fractures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of cryoablation of the intercostal nerves in providing pain relief for patients with multiple rib fractures. Participants will be compared to those receiving an ESP catheter for pain management. The primary outcome is pain control measured seven days post-procedure. The study aims to determine if cryoablation offers superior pain relief compared to the standard ESP catheter approach.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients who are over 18 who have more than one ribs fractured.

Exclusion Criteria:

* Patients who have an exclusion to regional anesthesia.
* Patients who are pregnant via self-report or pregnancy test if they take one.
* Non-English speakers
* Patients who have cold urticaria
* Patients with bilateral fractures
* Patients currently intubated

Where it's running

• University of Minnesota
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Neil Hanson — University of Minnesota
• Study coordinator: Candace Nelson
• Email: nelso377@umn.edu

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Breathing exercises to improve oxygenation after rib fractures

  This study tests whether breathing exercises can help patients with rib fractures breathe better and avoid complications while they recover in the intensive care unit.

  Recruiting Samsun University · Samsun · NCT06853002

• Using portable dynamic chest X-ray in the ICU

  This study is testing a new portable chest X-ray system in the ICU to see if it can give better pictures of lung movement and function compared to regular X-rays and CT scans for critically ill patients.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT06538376

• Breathing exercises for patients with rib fractures

  This study is testing if breathing exercises can help patients with rib fractures avoid lung problems better than just standard pain treatment.

  Recruiting Kastamonu University · Kastamonu · NCT06222333

• Freezing Nerves to Relieve Pain from Rib Fractures

  This study is testing if freezing the nerves can help people with rib fractures feel less pain compared to a fake treatment.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05865327

• Efficacy of continuous intercostal nerve block for patients with multiple rib fractures

  This study is testing if a continuous intercostal nerve block can provide better pain relief for people with multiple rib fractures compared to standard pain management options.

  Recruiting Phase 4 University of Kentucky · Lexington, Kentucky · NCT05642026

• Comparing low dose dexmedetomidine and ketamine for pain management in patients with multiple rib fractures

  This study is testing whether low dose dexmedetomidine or ketamine works better for managing pain in patients with multiple rib fractures while they are in the ICU.

  Recruiting Phase 3 Assiut University · Asyut, Assuit · NCT04928300

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.