Glucose levels during a 6 km loaded march
Glucose-Level During Endurance Exercise (GLEE Study): Influencing Factors and Mechanisms
We will test how blood sugar changes during a 6 km march carrying 15 kg of equipment in healthy soldiers using continuous glucose monitors.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Ulm Academic / other |
| Locations | 1 site (Ulm) |
| Trial ID | NCT07543705 on ClinicalTrials.gov |
What this trial studies
This observational study will recruit 100 healthy volunteer soldiers at the Bundeswehr Hospital Ulm and record metabolic and physiological data before, during, and after a standardized 6 km march with 15 kg of gear. Baseline measures include anthropometry, medical and lifestyle questionnaires (including the BSA physical activity questionnaire), body composition by bioelectrical impedance, and blood and urine sampling. Selected sensors including continuous glucose monitors and electrocardiography will be applied and calibrated, and physiological data will be collected continuously during the march. Additional blood and urine samples will be taken after the march to characterize acute metabolic responses.
Who should consider this trial
Good fit: Healthy adult soldiers serving at Bundeswehr Hospital Ulm with BMI 18.5–30 kg/m2 who are not pregnant, not lactating, and not taking medications that alter blood sugar or autonomic function are ideal candidates.
Not a fit: People with diabetes or on glucose‑altering medications, individuals with cardiovascular disease, pregnant or lactating people, those on a vegan diet, or anyone otherwise excluded for safety reasons are unlikely to be eligible or to benefit from this protocol.
Why it matters
Potential benefit: If successful, the findings could clarify how glucose fluctuates during loaded endurance activity and help refine fitness guidance and safety recommendations for soldiers.
How similar studies have performed: Previous work using continuous glucose monitoring during endurance exercise has provided useful data on glycemic responses, but studies specifically examining loaded military marches are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * BMI between 18.5 and 30 kg/m\^2 Exclusion Criteria: * Pregnancy or lactation * cardiovascular disease * vegan diet * drug or alcohol abuse * Drug therapy that raises or lowers blood sugar, e.g. steroids, antidiabetics, insulin or influences the autonomic nervous system * No consent to be informed about incidentally discovered pathological findings * Any other (clinical) condition that would endanger participants safety or question scientific success according to the physicians opinion.
Where this trial is running
Ulm
- Bundeswehr Hospital Ulm — Ulm, Germany (Recruiting)
Study contacts
- Principal investigator: Martin Heni, MD — University of Ulm
- Study coordinator: Martin Heni, MD
- Email: martin.heni@uniklinik-ulm.de
- Phone: +4973150044505
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.