Gerd symptoms with tegoprazan treatment in adults
Official title: A Multi-center, Prospective, Observational Study to Evaluate the Safety and Efficacy of K-CAB Tab./K-CAB ODT(Tegoprazan) in GERD Patients
Run by HK inno.N Corporation · NCT07678177 · Data updated 2026-11-12
This study tests whether tegoprazan 50 mg (tablet or dispersible tablet) helps GERD symptoms and is safe in adults who meet criteria.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 19 Years and up |
| Sex | All |
| Enrollment | 5384 (estimated) |
| Sponsor | HK inno.N Corporation Industry-sponsored |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | March 7, 2023 |
| Main results expected | June 30, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | July 1, 2026 |
| Trial ID | NCT07678177 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 19 years or older with GERD and a GerdQ score of 8 or higher, who voluntarily consent and are prescribed tegoprazan 50 mg in tablet or ODT form.
✕Probably not a fit
Patients who do not experience symptom improvement or who have adverse reactions to tegoprazan may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a multi-center, prospective observational study in adults with GERD who will be prescribed tegoprazan 50 mg in tablet or ODT form. Participants are observed to monitor safety and changes in symptoms over time without a mandated treatment protocol. Data will be collected from routine clinical care to describe real-world outcomes and tolerability. The study does not assign treatments but captures information from patients receiving tegoprazan as part of standard practice. It aims to provide practical insights into the safety profile and symptom improvement in a real-world setting.
Why it matters
Potential benefit: If successful, the study could clarify real-world safety and how well tegoprazan reduces GERD symptoms for patients.
How similar studies have gone: Observational experiences with similar acid-suppressant therapies have shown variable safety and symptom outcomes in real-world settings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Subjects over 19 years of age as of the date of consent 2. Subjects with a total score of 8 or more in the Korean Gastroesophageal Reflux Disease Questionnaire (GerdQ) based on Visit 1 3. Subjects who voluntarily decides to participate and agrees in writing to the consent form of the study Exclusion Criteria: 1. Subjects who have hypersensitivity reactions and a medical history of Benzimidazole or components of the investigational drug 2. Subjects on Atazanavir, Nelfinavir, or Rilpivirine-containing medications 3. Pregnant and lactating women
Where it's running
-
HK inno.N
Seoul, South Korea Recruiting
Study contacts
- Study coordinator: yong an jeong
- Email: yongan.jeong@inno-n.com
- Phone: 82-31-5176-4673
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.