Gastric Precancerous Epithelial Pathway in India Using High-Definition Endoscopy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicentre, cross-sectional analysis uses high-definition endoscopy and standardized pathology to estimate how often early gastric cancer and precancerous changes appear in an Indian patient population. It focuses on detecting cancers confined to the mucosa or submucosa (T1) and characterising precancerous lesions along the Correa pathway. The study is observational and collects data at a single time point across participating centers. It aims to fill gaps in multicentre data on prevalence and spectrum of early gastric cancer and precancerous conditions in India.

Why it matters

Who can join: the full rules

1. Adults aged ≥40 years undergoing upper gastrointestinal endoscopy for dyspepsia or other clinical indications (nonalarming and alarming symptoms both).
2. Ability to provide written informed consent.

Exclusion Criteria:

1. Known gastric malignancy.
2. Prior gastric surgery (excluding H. pylori eradication).
3. Contraindications to endoscopy or biopsy.
4. Known hereditary gastric cancer syndromes.

Where it's running

• AIG Hospitals
  Hyderabad, Telangana, India Recruiting

Study contacts

• Study coordinator: Dr.Hardik Rughwani Dr.Hardik Rughwani, MBBS, MD, DM
• Email: hardik.hr@gmail.com
• Phone: +91-9426928600

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.