Gait, daily activity, and sleep in people with Parkinson's

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will enroll 34 participants (17 with Parkinson's disease, Hoehn and Yahr stages 1–3, and 17 age-matched healthy controls) at Biruni University Hospital between January and May 2026. Gait will be recorded during a 3-meter sagittal-plane walk and analyzed with Kinovea to measure parameters like step length and arm swing, while balance will be measured with the Mini-BESTest. Physical capacity will be measured with a 2-Minute Walk Test and pulse oximetry, and daily step counts and sleep stages (deep, light, REM, wake) will be collected for one week via an Honor Choice wearable synced through the Wear Sync smartphone app; subjective sleep quality will be recorded with the Pittsburgh Sleep Quality Index. Data will be compared between the Parkinson's and control groups to determine whether observed impairments are disease-specific or related to aging.

Why it matters

Who can join: the full rules

Inclusion Criteria:

For Patients with Parkinson's Disease:

A confirmed diagnosis of Parkinson's disease according to the United Kingdom (UK) Brain Bank Criteria and classified as Hoehn and Yahr stages 1-3

Ability to walk independently on a flat surface without assistive devices (Functional Ambulation Scale ≥3)

Stable medication regimen during the past month

Being in the "on" phase of medication

For Healthy Individuals:

No diagnosis of neurological and/or neurodegenerative disease

Exclusion Criteria:

(For both Parkinson's patients and healthy individuals)

Severe hearing or visual impairments

Presence of other neurological, cardiovascular, or orthopedic conditions that may affect walking ability

Any additional neurological disorder (e.g., dementia, cerebrovascular disease)

Education level less than 5 years

Vascular pathologies affecting the lower extremities

Lack of smartphone use

Where it's running

• Biruni University Hospital
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Güzin Kaya Aytutuldu, phd
• Email: guzinkaya14@gmail.com
• Phone: 05366265884

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.