Gait, daily activity, and sleep in people with Parkinson's
The Relationship Between Balance and Gait Impairments, Physical Activity Level, and Sleep Quality in Parkinson's Disease
This project will test whether gait, daily activity, and sleep patterns differ between people aged 45–70 with Parkinson's and age-matched healthy adults.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 34 (estimated) |
| Ages | 40 Years to 75 Years |
| Sex | All |
| Sponsor | Biruni University Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT07424924 on ClinicalTrials.gov |
What this trial studies
This observational study will enroll 34 participants (17 with Parkinson's disease, Hoehn and Yahr stages 1–3, and 17 age-matched healthy controls) at Biruni University Hospital between January and May 2026. Gait will be recorded during a 3-meter sagittal-plane walk and analyzed with Kinovea to measure parameters like step length and arm swing, while balance will be measured with the Mini-BESTest. Physical capacity will be measured with a 2-Minute Walk Test and pulse oximetry, and daily step counts and sleep stages (deep, light, REM, wake) will be collected for one week via an Honor Choice wearable synced through the Wear Sync smartphone app; subjective sleep quality will be recorded with the Pittsburgh Sleep Quality Index. Data will be compared between the Parkinson's and control groups to determine whether observed impairments are disease-specific or related to aging.
Who should consider this trial
Good fit: Ideal candidates are people aged 45–70 with a UK Brain Bank-confirmed Parkinson's diagnosis at Hoehn and Yahr stages 1–3 who can walk independently, are in the 'on' medication phase with a stable regimen, and use a smartphone.
Not a fit: People with advanced Parkinson's (H&Y >3), dementia or other neurological/cardiovascular/orthopedic conditions that affect walking, severe hearing or vision loss, vascular lower-limb disease, low education (<5 years), or no smartphone use are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, the results could help clinicians target monitoring and interventions to improve mobility, sleep, and overall quality of life for people with Parkinson's.
How similar studies have performed: Wearable-based gait and sleep monitoring have shown useful results in prior Parkinson's research, though simultaneous combination of gait, balance, activity, and objective sleep metrics in a single small cohort is less common.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: For Patients with Parkinson's Disease: A confirmed diagnosis of Parkinson's disease according to the United Kingdom (UK) Brain Bank Criteria and classified as Hoehn and Yahr stages 1-3 Ability to walk independently on a flat surface without assistive devices (Functional Ambulation Scale ≥3) Stable medication regimen during the past month Being in the "on" phase of medication For Healthy Individuals: No diagnosis of neurological and/or neurodegenerative disease Exclusion Criteria: (For both Parkinson's patients and healthy individuals) Severe hearing or visual impairments Presence of other neurological, cardiovascular, or orthopedic conditions that may affect walking ability Any additional neurological disorder (e.g., dementia, cerebrovascular disease) Education level less than 5 years Vascular pathologies affecting the lower extremities Lack of smartphone use
Where this trial is running
Istanbul
- Biruni University Hospital — Istanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Güzin Kaya Aytutuldu, phd
- Email: guzinkaya14@gmail.com
- Phone: 05366265884
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.