Fungal microbiota in NSCLC and its clinical relevance

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will collect 500 lung tissue samples from NSCLC patients undergoing surgery to map the lung fungal community using high-throughput sequencing and traditional culture methods. They will integrate pathology, clinical data, and follow-up information to identify fungi associated with subtypes, stages, and prognosis. The study aims to build a fungal resource bank for NSCLC and explore potential roles of fungi in diagnosis and prognosis. This is an observational study without an active intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Non-small cell lung cancer was diagnosed by biopsy before operation, frozen pathology during operation or paraffin section after operation; The patients were 30 to 80 years old; No chemotherapy, radiotherapy, targeted therapy or immunotherapy were given before operation;

Exclusion Criteria:

Patients who do not meet the inclusion criteria; Combined with primary malignant tumor of other systems or recurrence of lung cancer, combined with immunodeficiency disease; Acute exacerbation of chronic obstructive pulmonary disease, bronchial asthma, bronchiectasis with infection, tuberculosis and pneumoconiosis; recent use of antifungal drugs; Basic clinical information (such as pathological type, clinical stage and treatment plan) cannot be obtained;

Where it's running

• 958th Army Hospital
  Chongqing, Liangjiang New, China Recruiting

Study contacts

• Study coordinator: shunhong wang project leader
• Email: wangshunhong918@163.com
• Phone: 023-68762084

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.