Cardiorespiratory fitness after lobectomy versus sublobar resection in NSCLC

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study that compares changes in cardiorespiratory fitness after two surgical approaches for NSCLC: lobectomy and sublobar resection (segmentectomy or wedge). CPET and pulmonary function tests are done before surgery and at 6 and 12 months after, with within-group and between-group comparisons. The study also explores how CPET results relate to postoperative complications. No procedures are assigned by the study; treatments occur as part of standard clinical care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1\. Able to understand the study and provide written informed consent. 2. Considered able to tolerate surgical treatment, including segmentectomy, lobectomy, or wedge resection, following preoperative assessment, including cardiac and pulmonary function testing.

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Exclusion Criteria:

1. Pregnant or breastfeeding.
2. Any absolute contraindication to CPET.
3. A history of severe heart disease, heart failure, myocardial infarction, or an episode of angina within the previous 3 months.
4. A cerebrovascular event, including cerebral infarction or cerebral hemorrhage, within the previous 3 months.
5. A psychiatric illness that prevents communication.
6. Unable to cooperate with the examinations. -

Where it's running

• Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
  Wuhan, Hubei, China Recruiting

Study contacts

• Study coordinator: Wei Ping
• Email: pingwei@tjh.tjmu.edu.cn
• Phone: 8613437101581

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.