Clinical trial Recruiting at 1 site Observational Ages 18 and up

Full-Contour Monolithic Zirconia Full-Mouth Implants: Post-Insertion Outcomes

Official title: Clinical Behavior of Full-Contour Monolithic Zirconia (FCMZ) Full-Mouth Implant Supported Rehabilitations: A Prospective Cohort Study

Run by Implantology Institute · NCT07876466 · Data updated 2026-11-12

This study tests how full-contour monolithic zirconia full-mouth implant restorations perform after at least one year in real-world patients.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorImplantology Institute
Academic / other
Locations1 site (Lisbon, Lisbon District)
StatusRecruiting
Main results expectedJuly 1, 2028
Study endsJuly 1, 2030
Registry record updatedOctober 20, 2026
Trial IDNCT07876466 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults receiving full-mouth implant-supported rehabilitations with full-contour monolithic zirconia and at least one year of follow-up.

Probably not a fit

Patients with ceramic veneers or non-full-mouth rehabilitations, or those unable to complete at least one year of follow-up, may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort tracks prosthodontic and biological complications after implant-supported full-mouth rehabilitations made from full-contour monolithic zirconia, without buccal veneers. Investigators calibrate assessments for complication types and aim for high inter-observer agreement. Data are collected from a private clinic in Lisbon, focusing on patients with at least one year of function. No magnification tools are used during evaluation, and the study follows patients receiving maxillary and/or mandibular full-mouth FC-MZ restorations.

Why it matters

Potential benefit: If successful, the study could clarify complication rates for FC-MZ full-mouth reconstructions, guiding clinicians in material choice and follow-up planning.

How similar studies have gone: Prior work on monolithic zirconia full-mouth rehabilitations has shown some favorable outcomes, but this specific independent prospective cohort is a newer, more focused evaluation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Maxilla and/or Mandible Implant full-mouth restoration
* Full-contour monolithic zirconia restoration (without ceramic veneer)
* be at least 18 years of age;
* present no systemic or local absolute contraindications for endosseous implant placement;
* at least 1 Year Follow-up

Exclusion Criteria:

* the presence of any systemic disease or condition that could compromise postoperative healing or osseointegration.
* Not full mouth rehabilitation
* Rehabilitations with ceramic veneers (buccal veneer or feldspathic veneered zirconia)

Where it's running

  • Instituto de Implantologia
    Lisbon, Lisbon District, Portugal
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.