Clinical trial Recruiting at 1 site Observational Ages 18 and up

Comparing different types of zirconia for full-mouth dental implants

Official title: Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior

Run by Implantology Institute · NCT01974362 · Data updated 2026-11-12

This study is testing how well different types of zirconia materials for full-mouth dental implants work over at least a year to see if they cause any problems for patients.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment90 (estimated)
SponsorImplantology Institute
Academic / other
Locations1 site (Lisbon, Lisbon District)
StatusRecruiting
StartedJanuary 2014
Main results expectedJanuary 1, 2028
Study endsDecember 31, 2029
Registry record updatedOctober 15, 2026
Trial IDNCT01974362 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older who require full-mouth implant restorations and have no contraindications for implant placement.

Probably not a fit

Patients with systemic diseases that could affect healing or those not undergoing full-mouth rehabilitation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the performance of full-mouth implant-supported rehabilitations using different types of zirconia materials: monolithic zirconia with a buccal veneer, full contour monolithic zirconia, and zirconia veneered with feldspathic ceramic. The study aims to assess prosthodontic and biological complications over a minimum follow-up period of one year. Data will be collected in a private clinic, with investigators calibrated to ensure high inter-observer agreement in assessments. The study will not utilize magnifying tools for recording complications.

Why it matters

Potential benefit: If successful, this study could lead to improved outcomes and reduced complications for patients receiving full-mouth dental implants.

How similar studies have gone: Previous studies have shown promising results with monolithic zirconia in dental applications, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Maxilla and/or Mandible Implant full-mouth restoration
* Monolithic ceramic or zirconia-feldspathic restoration
* be at least 18 years of age;
* present no systemic or local absolute contraindications for endosseous implant placement;
* at least 1 Year Follow-up

Exclusion Criteria:

* the presence of any systemic disease or condition that could compromise postoperative healing or osseointegration.
* Not full mouth rehabilitation

Where it's running

  • Artur Simões
    Lisbon, Lisbon District, Portugal
    Recruiting

Study contacts

  • Principal investigator: Artur Simões, Msc — Implantology Institute

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.