fNIRS-guided visual feedback training to improve walking after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with hemiplegic stroke will be randomly assigned to receive either an intelligent visual-feedback lower-limb motor control program using the MRS-FS system or conventional Bobath ball training. Therapies are delivered at Shengjing Hospital's rehabilitation center with task-oriented, gamified exercises designed to improve knee control and overall lower-limb coordination. Three-dimensional gait analysis will provide precise quantitative measures of walking mechanics, while functional near-infrared spectroscopy (fNIRS) will measure cortical activation and functional connectivity before and after the intervention. Outcomes will compare changes in walking function and analyze correlations between fNIRS signals and gait improvements.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1: Vital signs are stable, with no severe cardiopulmonary diseases, making the patient suitable for exercise testing.

  2: All patients are diagnosed with stroke by head CT or MRI, with clinical manifestations of unilateral limb hemiplegia.

  3: The Brunnstrom stage of the lower limb is 3-5, quadriceps muscle strength is ≥ grade 3, modified Ashworth scale for the lower limb is \< grade 2, and Hoffer walking scale is ≥ grade 2.

  4: This is their first onset of the disease, with a disease course of ≤ 6 months, and the condition is stable.

  5: Patients have no severe cognitive impairment or sensory aphasia, can understand and actively participate in the training program, and have provided informed consent by signing the consent form for this clinical study.

  6: Age: 18-75 years old, no gender restrictions.

Exclusion Criteria:

* 1: Patients with tumors, tuberculosis, hematological diseases, or functional impairments of vital organs such as the heart or liver.

  2: Those with lower limb musculoskeletal disorders, such as knee arthritis or lower limb fractures.

  3: Individuals with severe abnormal muscle tone in the limbs or joint contracture deformities.

  4: Patients experiencing severe pain that prevents them from tolerating physical activity.

  5: Special populations, such as individuals with mental illnesses, breastfeeding women, or pregnant women.

Where it's running

• Rehabilitation Center of Shengjing Hospital, China Medical University
  Shenyang, Liaoning, China Recruiting

Study contacts

• Study coordinator: Xue Jiang
• Email: jiangxueruby@163.com
• Phone: +8618940254064

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.