Clinical trial Recruiting at 1 site Observational Ages 18 and up

Finding the blocked artery in medium-vessel stroke using multiple CT scans

Official title: Study on the Accuracy of Determining the Responsible Vessel in Medium Vessel Occlusive Stroke Based on Multi-type CT Evaluation

Run by Xuanwu Hospital, Beijing · NCT07347587 · Data updated 2026-11-12

We will see if using multiple types of CT scans (noncontrast CT, CTA, and CT perfusion) can accurately identify the specific artery causing a medium-vessel ischemic stroke in adults within 24 hours of symptom onset.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment622 (estimated)
SponsorXuanwu Hospital, Beijing
Academic / other
Locations1 site (Beijing, Beijing Municipality)
StatusRecruiting
StartedMarch 13, 2025
Main results expectedMarch 13, 2026
Study endsMarch 13, 2026
Registry record updatedJanuary 16, 2026
Trial IDNCT07347587 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 or older with acute ischemic stroke, treated within 24 hours of last-well time, who had pre-treatment CT, CTA, and CTP with complete clinical and DICOM imaging data are ideal candidates.

Probably not a fit

Patients with acute intracranial hemorrhage, poor-quality or missing DICOM imaging files, or CTP images that cannot be post-processed are unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational imaging study enrolling adults with acute ischemic stroke who received pre-treatment noncontrast CT, CT angiography (CTA), and CT perfusion (CTP) within 24 hours of last-well time. Original CTP images will be post-processed and multimodal CT data (including DICOM files) will be reviewed to determine the responsible vessel in cases of medium-vessel occlusion. Cases with complete clinical and imaging records will be included, while those with intracranial hemorrhage or unusable image data will be excluded. The accuracy of artery attribution by multimodal CT will be compared with available clinical imaging records and follow-up imaging when available.

Why it matters

Potential benefit: If successful, this approach could help clinicians more quickly and precisely identify the specific artery causing a medium-vessel stroke, which may improve selection and planning of treatments.

How similar studies have gone: Multimodal CT and CT perfusion have been useful for identifying large-vessel occlusions, but their specific accuracy for pinpointing responsible arteries in medium-vessel occlusion is less well-established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with acute ischemic stroke, without restrictions on gender
* Age ≥ 18 years old
* The time from onset to treatment is within 24 hours (the onset time is defined as the "last-well-time", and the treatment plan is determined according to the patient's wishes and local clinical experience)
* Before the treatment, CT, CTA and CTP examinations were conducted, and the relevant clinical data were complete.

Exclusion Criteria:

* Patients with acute intracranial hemorrhage
* Patients whose CTP original images cannot be processed by the CTP post-processing software
* Patients for whom the DICOM format image data of CT, CTP original images and MRI images cannot be obtained, or whose image quality is poor due to various reasons

Where it's running

  • Xuanwu Hospital Capital Medical University
    Beijing, Beijing Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.