Finding the blocked artery in medium-vessel stroke using multiple CT scans
Official title: Study on the Accuracy of Determining the Responsible Vessel in Medium Vessel Occlusive Stroke Based on Multi-type CT Evaluation
Run by Xuanwu Hospital, Beijing · NCT07347587 · Data updated 2026-11-12
We will see if using multiple types of CT scans (noncontrast CT, CTA, and CT perfusion) can accurately identify the specific artery causing a medium-vessel ischemic stroke in adults within 24 hours of symptom onset.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 622 (estimated) |
| Sponsor | Xuanwu Hospital, Beijing Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | March 13, 2025 |
| Main results expected | March 13, 2026 |
| Study ends | March 13, 2026 |
| Registry record updated | January 16, 2026 |
| Trial ID | NCT07347587 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with acute ischemic stroke, treated within 24 hours of last-well time, who had pre-treatment CT, CTA, and CTP with complete clinical and DICOM imaging data are ideal candidates.
✕Probably not a fit
Patients with acute intracranial hemorrhage, poor-quality or missing DICOM imaging files, or CTP images that cannot be post-processed are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational imaging study enrolling adults with acute ischemic stroke who received pre-treatment noncontrast CT, CT angiography (CTA), and CT perfusion (CTP) within 24 hours of last-well time. Original CTP images will be post-processed and multimodal CT data (including DICOM files) will be reviewed to determine the responsible vessel in cases of medium-vessel occlusion. Cases with complete clinical and imaging records will be included, while those with intracranial hemorrhage or unusable image data will be excluded. The accuracy of artery attribution by multimodal CT will be compared with available clinical imaging records and follow-up imaging when available.
Why it matters
Potential benefit: If successful, this approach could help clinicians more quickly and precisely identify the specific artery causing a medium-vessel stroke, which may improve selection and planning of treatments.
How similar studies have gone: Multimodal CT and CT perfusion have been useful for identifying large-vessel occlusions, but their specific accuracy for pinpointing responsible arteries in medium-vessel occlusion is less well-established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with acute ischemic stroke, without restrictions on gender * Age ≥ 18 years old * The time from onset to treatment is within 24 hours (the onset time is defined as the "last-well-time", and the treatment plan is determined according to the patient's wishes and local clinical experience) * Before the treatment, CT, CTA and CTP examinations were conducted, and the relevant clinical data were complete. Exclusion Criteria: * Patients with acute intracranial hemorrhage * Patients whose CTP original images cannot be processed by the CTP post-processing software * Patients for whom the DICOM format image data of CT, CTP original images and MRI images cannot be obtained, or whose image quality is poor due to various reasons
Where it's running
-
Xuanwu Hospital Capital Medical University
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Shujuan Meng, MD
- Email: 1026012717@qq.com
- Phone: 01083198082
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
-
Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
-
AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
-
Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
-
Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
-
Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.