Fasting to Treat Long Covid in Adults
Official title: Pilot Study on the Feasibility of an RCT: Evaluating Periodic Fasting as a Treatment Strategy for Long Covid in Adults
Run by University of Luxembourg · NCT06522750 · Data updated 2026-11-12
This study is testing if a week of fasting can help adults with long COVID feel better by reducing inflammation and improving their health.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 64 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | University of Luxembourg Academic / other |
| Locations | 1 site (Ettelbruck) |
| Status | Recruiting |
| Started | February 19, 2025 |
| Main results expected | June 30, 2025 |
| Study ends | September 30, 2025 |
| Registry record updated | March 30, 2025 |
| Trial ID | NCT06522750 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18-64 who have been diagnosed with long COVID syndrome and have a normal body mass index.
✕Probably not a fit
Patients with severe internal diseases, current eating disorders, or those who are underweight may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot study investigates the feasibility of a 7-day ambulatory fasting intervention using the Buchinger-Wilhelmi method for adults suffering from long COVID. The study aims to assess how fasting may modulate immune responses and improve health outcomes in patients experiencing persistent symptoms following COVID-19 infection. By focusing on chronic inflammation associated with long COVID, the research seeks to explore the potential therapeutic benefits of caloric restriction on symptom relief and overall well-being.
Why it matters
Potential benefit: If successful, this intervention could provide a novel dietary approach to alleviate long COVID symptoms and improve patients' quality of life.
How similar studies have gone: While dietary interventions like fasting have shown promise in other conditions, this specific approach for long COVID is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-64 * Diagnosis Long Covid Syndrome (post-acute COVID-19 symptoms persisting ≥12 weeks) * Normal body Mass Index (18.5 to 25 kg/m2) * Marginal Iron status ( PF\< 25 ng/ml) * Able to communicate in and comprehend English and/or German and/or French language * Present written / signed declaration of consent * Ability to understand the patient information and willingness to sign the consent form * Consent to specimen collection and specimen use Exclusion Criteria: * Current underweight condition (body mass index less than 18.5 kg/m2) or weight loss exceeding 3 kg within the last month or 5 kg within the last three months. * Existing / current eating disorder within the past five years (e.g., anorexia, bulimia). * Psychiatric condition that limits understanding of the examination protocol (unable to consent) * Severe internal disease (e.g. kidney deficiency with creatinine \> 2mg/dl), chronic inflammatory illness other than LCS * Participation in another intervention study. * Existing vegan diet or fasting during the last six months * Pregnancy or breastfeeding status. * Presence or suspicion of pre-existing ME/CFS or early autonomous dysfunction * Diagnosis of chronic inflammatory bowel diseases, celiac disease or colorectal cancer according to the guidelines of the German Society of Gastroenterology * Use of anti-psychotic drugs * Antibiotic use during the previous 12 months * Start of novel drug therapy * Contraindication for additional blood draws (e.g. hemoglobin \<10)
Where it's running
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Rehaklinik CHNP
Ettelbruck, Luxembourg Recruiting
Study contacts
- Principal investigator: Raquel Gomez Bravo, PhD — Rehaklinik du Centre Hospitalier Neuro-Psychiatrique (CHNP), UL
- Study coordinator: Marta Sanchez, PhD
- Email: marta.sanchez@uni.lu
- Phone: +3524666446555
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Whole-body Cryotherapy for Fatigue in ME/CFS, Fibromyalgia, Long COVID
This study tests whether brief, repeated exposure to extreme cold can help reduce fatigue and related symptoms in adults with ME/CFS, fibromyalgia, or Long COVID compared to healthy controls.
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Fatigue Investigation Using Digital Outcomes
This study tests whether digital monitoring with a smartphone app and wearables can track fatigue in people with MS or long COVID, compared with healthy volunteers.
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Biomarker study to understand Long COVID using VIPER
This study tests biomarkers in people with Long COVID and those who recovered from COVID-19 to see how they can diagnose and track the condition over time.
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PERCEIVE-Outreach: A scalable care model to help people with Long COVID manage heart and lung symptoms
This study tests a remote care model to see if a personalized, telehealth-based exercise program helps adults with Long COVID feel better and move more.
-
Testing PNMR plus standard care for long COVID
We’re trying PNMR along with standard care to see if it helps people with long COVID better than standard care alone.
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Combination therapy for Long COVID symptoms using valacyclovir, celecoxib, and Paxlovid
This study tests whether a three-drug combination can reduce Long COVID symptoms in adults compared with a placebo.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.