Clinical trial Recruiting at 1 site Observational Ages 18 and up

Factors influencing exacerbation and mortality in bronchiectasis patients in Hong Kong

Official title: A Prospective Study of Factors Related to Exacerbation and Mortality of Non-cystic Fibrosis Bronchiectasis in Hong Kong

Run by Chinese University of Hong Kong · NCT04538859 · Data updated 2026-11-12

This study looks at what causes flare-ups and deaths in adults with bronchiectasis in Hong Kong to better understand how to manage their condition.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment400 (estimated)
SponsorChinese University of Hong Kong
Academic / other
Locations1 site (Hong Kong, Please Select)
StatusRecruiting
StartedAugust 30, 2020
Main results expectedAugust 29, 2027
Study endsAugust 29, 2027
Registry record updatedSeptember 4, 2020
Trial IDNCT04538859 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 years or older who have a diagnosis of bronchiectasis and have been clinically stable for at least four weeks.

Probably not a fit

Patients with a history of cystic fibrosis, hypogammaglobulinemia, or allergic bronchopulmonary aspergillosis may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the factors related to exacerbation and mortality in adults with non-cystic fibrosis bronchiectasis in Hong Kong. It will assess the prevalence, clinical presentation, and outcomes of bronchiectasis, which is characterized by repeated exacerbations leading to increased hospital admissions and healthcare costs. The study will involve patients who are clinically stable and have a confirmed diagnosis of bronchiectasis through high-resolution computed tomography. The findings will help inform management plans for this condition.

Why it matters

Potential benefit: If successful, this study could provide valuable insights that lead to improved management strategies and outcomes for patients with bronchiectasis.

How similar studies have gone: While there have been previous studies on bronchiectasis, this study aims to provide updated prevalence and characteristics, making it a novel approach in the local context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients aged 18 years or older
2. Clinically stable for at least 4 weeks prior to enrollment (defined as no symptoms of exacerbation, no requirement for supplemental antibiotic therapy)
3. Diagnosis of bronchiectasis defined by high-resolution computed tomography scan

Exclusion Criteria:

1. History of cystic fibrosis; hypogammaglobulinemia; allergic bronchopulmonary aspergilosis
2. Those who are unable to give consent

Where it's running

  • Chinese University of Hong
    Hong Kong, Please Select, Hong Kong
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.