Home use of the LibAirty airway clearance system for adults with bronchiectasis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-arm, open-label observational study follows adults with CT-confirmed bronchiectasis who are already prescribed the LibAirty system for home use. Participants will be followed for 12 months while they continue their usual care, with outcomes compared to each participant's prior 12 months as a historical control. Up to four routine clinic visits will collect medical record data, validated symptom and quality-of-life questionnaires, and device usage logs to measure adherence. The study does not provide the device and does not change prescribing or standard clinical care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Have a radiological diagnosis of Bronchiectasis based on high resolution chest CT scan
2. Have bronchiectasis characterized by either:

   * Daily productive cough (as determined by a treating physician)
   * OR Available documentation from the last 12 months of 2 or more pulmonary exacerbations requiring antibiotic therapy
3. Be at age ≥ 21 years
4. Prescribed and receives the LibAirty system for home use
5. Be on a standard of care treatment plan that includes at least one physician encounter every 6 months
6. No change in treatment for Bronchiectasis in the 2-month period prior to enrollment
7. Signed informed consent

Exclusion Criteria:

1. Inability to independently perform therapy with the LibAirty system as directed
2. Any other condition that, in the opinion of the PI, could jeopardize the safety of the subject or impact the validity of the study results.
3. Pregnancy or planned pregnancy during the expected duration of the trial (12 months).

Where it's running

• University of Alabama at Birmingham
  Birmingham, Alabama, United States Recruiting
• Emory University School Of Medicine
  Atlanta, Georgia, United States Recruiting
• Medical University of South Carolina
  Charleston, South Carolina, United States Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.