Exploring the role of vitamin status and epigenetics in severe obesity
Influence of Vitamins Status on Severe Obesity Related Complications
This study is trying to see how vitamin levels and genetic factors affect health problems in people with severe obesity who are considering weight loss surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20000 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | University of Lorraine Academic / other |
| Locations | 1 site (Vandoeuvre Les Nancy) |
| Trial ID | NCT02663388 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate how vitamin levels and epigenetic factors contribute to complications associated with severe obesity. It focuses on patients who are candidates for bariatric surgery, including procedures like gastric bypass, sleeve gastrectomy, and gastric banding. By collecting biological tissue samples, the study seeks to understand the underlying mechanisms that may influence obesity-related health issues such as diabetes and non-alcoholic fatty liver disease.
Who should consider this trial
Good fit: Ideal candidates are individuals with a BMI greater than 35 kg/m2 who are indicated for bariatric surgery.
Not a fit: Patients who are unable to provide informed consent or refuse to participate will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of severe obesity and its complications.
How similar studies have performed: While the specific approach of this study may be novel, other studies have explored the relationship between epigenetics and obesity, showing promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * indication for bariatric surgery with BMI \> 35 kg/m2 Exclusion Criteria: * unable to receive clear information * refusal to sign the consent form
Where this trial is running
Vandoeuvre Les Nancy
- University of Lorraine, CHU Nancy — Vandoeuvre Les Nancy, France (Recruiting)
Study contacts
- Principal investigator: laurent BRUNAUD, MD, PhD — University of Lorraine, CHU Nancy
- Study coordinator: Laurent BRUNAUD, MD, PhD
- Email: l.brunaud@chu-nancy.fr
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.