Clinical trial Recruiting at 1 site Observational Ages 18 to 100

Exploring the link between stroke and adrenal incidentalomas

Official title: If Adrenal Incidentalomas Have the Influences to Occur and Progress in Patients With Stroke

Run by Xuanwu Hospital, Beijing · NCT05237817 · Data updated 2026-11-12

This study is trying to see if having adrenal incidentalomas affects the risk of disability and death in stroke patients.

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment2 (estimated)
SponsorXuanwu Hospital, Beijing
Academic / other
Locations1 site (Beijing)
StatusRecruiting
StartedApril 1, 2021
Main results expectedApril 1, 2022
Study endsFebruary 28, 2029
Registry record updatedFebruary 14, 2022
Trial IDNCT05237817 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with stroke, including those with cerebral infarction, intracerebral hemorrhage, or subarachnoid hemorrhage.

Probably not a fit

Patients with metastatic cancer, adrenal incidentalomas smaller than 1 cm, or those on specific glucocorticoid treatments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the association between adrenal incidentalomas (AIs) and stroke, focusing on the risk of disability and death in stroke patients with AIs. It consists of two parts: a retrospective cohort study analyzing data from stroke patients between April and September 2021, and a prospective cohort study recruiting stroke patients from March 2022 to February 2024. The study aims to measure levels of autonomous cortisol secretion in these patients and assess the standardized incidence rate of AIs. Detailed information regarding stroke characteristics and patient profiles will be recorded throughout the study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the risks associated with adrenal incidentalomas in stroke patients, potentially guiding better management and treatment strategies.

How similar studies have gone: While the association between adrenal incidentalomas and stroke is not extensively studied, this investigation aims to fill a gap in existing literature, making it a novel approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* stroke disease , such as Cerebral infarction、Intracerebral hemorrhage and Subarachnoid hemorrhage.

Exclusion Criteria:

* presence of metastatic cancer;
* AIs smaller than 1 cm;
* nonadenoma lesions, such as myelolipomas,hemorrhages, and cysts;
* oral glucocorticoid treatment with more than single doses in the past 3 months;
* use of inhaled steroids or medication affecting dexamethasone metabolism;
* systemic estrogen treatment.

Where it's running

  • Hao Yan
    Beijing, China
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.