Exploring the link between sleep apnea, facial discoloration, and fainting symptoms.

Clinical Association Between Obstructive Sleep Apnea (OSA) and Facial Pigmentation, and the Relation Between OSA and Vasovagal Symptoms With Resulting Smoking Tendency and the Effect of Treatment in Patients Referred for Sleep Study.

Observational Jordan Collaborating Cardiology Group · NCT06331819

This study is trying to see if changes in facial color can help identify sleep apnea in people who also experience fainting symptoms and smoke.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorJordan Collaborating Cardiology Group Academic / other
Locations1 site (Amman)
Trial IDNCT06331819 on ClinicalTrials.gov

What this trial studies

This observational study aims to gather demographic and clinical data from patients referred for sleep studies at the Jordan University Hospital and other locations. It will assess the diagnostic value of facial discoloration as a potential indicator of obstructive sleep apnea (OSA) and explore the relationship between OSA, vasovagal symptoms, and smoking tendencies. Participants will undergo polysomnography and will be followed up to evaluate treatment outcomes and symptom improvement over time.

Who should consider this trial

Good fit: Ideal candidates include individuals referred for sleep studies who are within the specified age range and consent to participate.

Not a fit: Patients with a prior diagnosis of obstructive sleep apnea will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the detection of obstructive sleep apnea and improve management strategies for patients exhibiting related symptoms.

How similar studies have performed: While the approach of correlating facial discoloration with obstructive sleep apnea is relatively novel, similar studies have shown promise in identifying diagnostic markers for sleep disorders.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients within age limit who agree to participate and sign the consent form.

Exclusion Criteria:

* Patients with prior diagnosis of obstructive sleep apnea by sleep study.

Where this trial is running

Amman

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obstructive Sleep ApneaVasovagal SyncopeSmokingAcanthosis NigricansFacial DiscolorationSmoking CessationJordanIn-Lab Polysomnography
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.