Clinical trial Recruiting at 1 site Observational Ages 16 to 99

Exploring the impact of blunt adrenal gland injuries in trauma patients

Official title: Exploring the Epidemiology and Burden of Blunt Adrenal Gland Injury in the Context of Major Trauma

Run by Niguarda Hospital · NCT06220448 · Data updated 2026-11-12

This study looks at how injuries to the adrenal glands affect recovery and survival in adults who have experienced blunt trauma to the chest and abdomen.

More Trauma Injury trials

Quick facts

Study typeObservational
Ages16 Years to 99 Years
SexAll
Enrollment5000 (estimated)
SponsorNiguarda Hospital
Academic / other
Locations1 site (Miano, Lombardy)
StatusRecruiting
StartedJanuary 1, 2024
Main results expectedJune 30, 2026
Study endsSeptember 30, 2027
Registry record updatedApril 16, 2026
Trial IDNCT06220448 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 16 years old who have experienced blunt thoraco-abdominal trauma.

Probably not a fit

Patients with traumatic brain injuries classified as severe or those who have isolated brain or spinal cord injuries may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the outcomes of adult patients who have sustained blunt thoraco-abdominal trauma, focusing specifically on those with adrenal gland injuries. By analyzing a multicenter cohort, the study aims to clarify the relationship between the severity of trauma and the presence of adrenal gland injuries, which have shown variable outcomes in existing literature. The research will utilize data from CT scans and surgical findings to assess the clinical burden of these injuries and their implications on patient survival and recovery. The primary endpoint is to compare trauma severity between patients with and without adrenal gland injuries.

Why it matters

Potential benefit: If successful, this study could provide clearer insights into the implications of adrenal gland injuries in trauma patients, potentially guiding treatment protocols.

How similar studies have gone: While there have been studies on trauma outcomes, this specific focus on blunt adrenal gland injuries in a homogeneous trauma population is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* Age \> 16 years old
* All patients with blunt thoraco-abdominal trauma

Exclusion criteria:

* TBI with AIS \> 3
* Isolated TBI and Spinal cord injury
* Patients died in emergency department

Where it's running

  • ASST GOM Niguarda
    Miano, Lombardy, Italy
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.