Exploring the impact of blunt adrenal gland injuries in trauma patients
Exploring the Epidemiology and Burden of Blunt Adrenal Gland Injury in the Context of Major Trauma
This study looks at how injuries to the adrenal glands affect recovery and survival in adults who have experienced blunt trauma to the chest and abdomen.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 16 Years to 99 Years |
| Sex | All |
| Sponsor | Niguarda Hospital Academic / other |
| Locations | 1 site (Miano, Lombardy) |
| Trial ID | NCT06220448 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the outcomes of adult patients who have sustained blunt thoraco-abdominal trauma, focusing specifically on those with adrenal gland injuries. By analyzing a multicenter cohort, the study aims to clarify the relationship between the severity of trauma and the presence of adrenal gland injuries, which have shown variable outcomes in existing literature. The research will utilize data from CT scans and surgical findings to assess the clinical burden of these injuries and their implications on patient survival and recovery. The primary endpoint is to compare trauma severity between patients with and without adrenal gland injuries.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 16 years old who have experienced blunt thoraco-abdominal trauma.
Not a fit: Patients with traumatic brain injuries classified as severe or those who have isolated brain or spinal cord injuries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide clearer insights into the implications of adrenal gland injuries in trauma patients, potentially guiding treatment protocols.
How similar studies have performed: While there have been studies on trauma outcomes, this specific focus on blunt adrenal gland injuries in a homogeneous trauma population is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Age \> 16 years old * All patients with blunt thoraco-abdominal trauma Exclusion criteria: * TBI with AIS \> 3 * Isolated TBI and Spinal cord injury * Patients died in emergency department
Where this trial is running
Miano, Lombardy
- ASST GOM Niguarda — Miano, Lombardy, Italy (Recruiting)
Study contacts
- Study coordinator: Stefano P Cioffi, MD
- Email: stefanopiero.cioffi@ospedaleniguarda.it
- Phone: +3386032519
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.