Regional anesthesia techniques for pain control after pelvic and acetabular fracture surgery
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study. Pain Management in Surgical and Conservative Settings."
This study will try regional anesthesia techniques to see if they lower pain and opioid use after pelvic or acetabular fracture surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | A.O.U. Città della Salute e della Scienza Academic / other |
| Locations | 1 site (Turin) |
| Trial ID | NCT07072286 on ClinicalTrials.gov |
What this trial studies
This is a prospective, monocentric observational pilot cohort enrolling adults undergoing surgery for pelvic or acetabular fractures who receive regional anesthesia within a multimodal analgesia plan. Pain intensity will be recorded at predefined time points in the first 48 hours and opioid consumption quantified in the first 24 hours, while investigators will document complications and adverse events. The team will also monitor the onset of persistent post-surgical pain and track functional recovery at 30, 60, and 90 days. Patients with absolute contraindications to regional anesthesia (for example uncorrectable coagulopathy or allergy to local anesthetics) are excluded.
Who should consider this trial
Good fit: Adults (≥18 years) with pelvic or acetabular fractures who require surgery, can provide informed consent, and have no contraindications to regional anesthesia are the ideal candidates.
Not a fit: Patients under 18, those with absolute contraindications to regional anesthesia (uncorrectable coagulopathy, known allergy to local anesthetics), or cases where regional techniques cannot be performed are unlikely to benefit from this approach.
Why it matters
Potential benefit: If successful, this approach could reduce early postoperative pain and opioid requirements and may lower complication rates and the risk of long-term persistent pain after pelvic fracture surgery.
How similar studies have performed: Regional anesthesia and peripheral nerve blocks have demonstrated reduced pain and opioid use after hip and lower-extremity fractures, but robust data specifically for pelvic and acetabular fracture surgery are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years and ability to provide informed consent * Patients with pelvic/acetabular fractures requiring surgery Exclusion Criteria * Age \< 18 years * Absolute contraindications to ALR techniques (uncorrectable coagulopathies, known allergy to local anesthetics, technical impossibility of execution)
Where this trial is running
Turin
- Centro Traumatologico Ortopedico (CTO) - AOU Città della Salute e della Scienza Univeristy Hospital — Turin, Italy (Recruiting)
Study contacts
- Study coordinator: Marco Ulla, MD
- Email: marco.ulla@gmail.com
- Phone: +39-3397548673
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.