Exploring Red Blood Cell Disorders
Official title: Pathophysiological Explorations of Red Blood Cells
Run by Imagine Institute · NCT03541525 · Data updated 2026-11-12
This study is trying to learn more about red blood cell disorders by collecting samples from people with these conditions or their family members to help create better treatments.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 3750 (estimated) |
| Sponsor | Imagine Institute Academic / other |
| Locations | 25 sites (Cotonou and 24 other locations) |
| Status | Recruiting |
| Started | October 16, 2017 |
| Main results expected | October 15, 2037 |
| Study ends | October 15, 2037 |
| Registry record updated | September 9, 2026 |
| Trial ID | NCT03541525 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals affected by red blood cell disorders or those with a family history of these conditions.
✕Probably not a fit
Patients who are deprived of freedom will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational program, GR-Ex, is designed to enhance understanding of red blood cell physiology, erythropoiesis, and iron metabolism. It involves biological sampling from participants who have red blood cell disorders or a family history of such conditions. The initiative aims to develop innovative therapeutic protocols that could improve treatment outcomes for these disorders. The study is supported by the French Ministry of Higher Education and Research as part of a Laboratory of Excellence program.
Why it matters
Potential benefit: If successful, this program could lead to new therapeutic approaches for patients with red blood cell disorders.
How similar studies have gone: Other studies focusing on red blood cell disorders have shown promise in understanding and treating these conditions, indicating that this approach is building on existing knowledge.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * To be affected or have a family history of disease bound to the red blood cell, * For adult subjects, have signed an informed consent form, * For minor or major under legal safeguard subjects, the form must be signed by both parents (for minors) or by the legal representative, * Be affiliated to health insurance. Exclusion Criteria: * Being deprived of freedom
Where it's running
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CHU Amiens-Picardie
Amiens, France Recruiting -
Hôpital Privé d'Antony
Antony, France Recruiting -
Hôpital Avicenne
Bobigny, France Recruiting -
Hôpital Pellegrin
Bordeaux, France Recruiting -
Hôpital Beaujon
Clichy, France Recruiting -
Hôpital Louis Mourier
Colombes, France Recruiting
Show 19 more locations
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Hopital Henri Mondor
Créteil, France Recruiting -
CHU Kremlin Bicetre
Le Kremlin-Bicêtre, France Recruiting -
Hopital de la conception
Marseille, France Recruiting -
Hôpital d'Enfants de la TIMONE
Marseille, France Recruiting -
Hôpital Saint Eloi
Montpellier, France Recruiting -
CHU de Niort
Niort, France Recruiting -
Groupe Hospitalier Diaconesses Croix Saint Simon
Paris, France Recruiting -
Hopital Necker - Enfants malades
Paris, France Recruiting -
Hôpital Armand Trousseau
Paris, France Recruiting -
Hôpital Cochin
Paris, France Recruiting -
Hôpital Européen Georges-Pompidou
Paris, France Recruiting -
Hôpital Saint Louis
Paris, France Recruiting -
Hôpital Saint-Antoine
Paris, France Recruiting -
Institut Pasteur
Paris, France Recruiting -
CHU de Rouen
Rouen, France Recruiting -
Hôpital national d'instruction des armées Bégin
Saint-Mandé, France Recruiting -
CHU Hôpital de la Mère et de l'enfant Lagune
Cotonou, Benin Not yet recruiting -
Hôpital Robert Debré
Paris, France Not yet recruiting -
CHU de la Guadeloupe
Pointe-à-Pitre, Guadeloupe Not yet recruiting
Study contacts
- Study coordinator: Sandra Manceau, PhD
- Email: sandra.manceau@aphp.fr
- Phone: +33171196435
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.