Clinical trial Recruiting at 22 sites Observational

Exploring Red Blood Cell Disorders

Official title: Pathophysiological Explorations of Red Blood Cells

Run by Imagine Institute · NCT03541525 · Data updated 2026-11-12

This study is trying to learn more about red blood cell disorders by collecting samples from people with these conditions or their family members to help create better treatments.

Quick facts

Study typeObservational
SexAll
Enrollment3750 (estimated)
SponsorImagine Institute
Academic / other
Locations25 sites (Cotonou and 24 other locations)
StatusRecruiting
StartedOctober 16, 2017
Main results expectedOctober 15, 2037
Study endsOctober 15, 2037
Registry record updatedSeptember 9, 2026
Trial IDNCT03541525 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals affected by red blood cell disorders or those with a family history of these conditions.

Probably not a fit

Patients who are deprived of freedom will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational program, GR-Ex, is designed to enhance understanding of red blood cell physiology, erythropoiesis, and iron metabolism. It involves biological sampling from participants who have red blood cell disorders or a family history of such conditions. The initiative aims to develop innovative therapeutic protocols that could improve treatment outcomes for these disorders. The study is supported by the French Ministry of Higher Education and Research as part of a Laboratory of Excellence program.

Why it matters

Potential benefit: If successful, this program could lead to new therapeutic approaches for patients with red blood cell disorders.

How similar studies have gone: Other studies focusing on red blood cell disorders have shown promise in understanding and treating these conditions, indicating that this approach is building on existing knowledge.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* To be affected or have a family history of disease bound to the red blood cell,
* For adult subjects, have signed an informed consent form,
* For minor or major under legal safeguard subjects, the form must be signed by both parents (for minors) or by the legal representative,
* Be affiliated to health insurance.

Exclusion Criteria:

* Being deprived of freedom

Where it's running

  • CHU Amiens-Picardie
    Amiens, France
    Recruiting
  • Hôpital Privé d'Antony
    Antony, France
    Recruiting
  • Hôpital Avicenne
    Bobigny, France
    Recruiting
  • Hôpital Pellegrin
    Bordeaux, France
    Recruiting
  • Hôpital Beaujon
    Clichy, France
    Recruiting
  • Hôpital Louis Mourier
    Colombes, France
    Recruiting
Show 19 more locations
  • Hopital Henri Mondor
    Créteil, France
    Recruiting
  • CHU Kremlin Bicetre
    Le Kremlin-Bicêtre, France
    Recruiting
  • Hopital de la conception
    Marseille, France
    Recruiting
  • Hôpital d'Enfants de la TIMONE
    Marseille, France
    Recruiting
  • Hôpital Saint Eloi
    Montpellier, France
    Recruiting
  • CHU de Niort
    Niort, France
    Recruiting
  • Groupe Hospitalier Diaconesses Croix Saint Simon
    Paris, France
    Recruiting
  • Hopital Necker - Enfants malades
    Paris, France
    Recruiting
  • Hôpital Armand Trousseau
    Paris, France
    Recruiting
  • Hôpital Cochin
    Paris, France
    Recruiting
  • Hôpital Européen Georges-Pompidou
    Paris, France
    Recruiting
  • Hôpital Saint Louis
    Paris, France
    Recruiting
  • Hôpital Saint-Antoine
    Paris, France
    Recruiting
  • Institut Pasteur
    Paris, France
    Recruiting
  • CHU de Rouen
    Rouen, France
    Recruiting
  • Hôpital national d'instruction des armées Bégin
    Saint-Mandé, France
    Recruiting
  • CHU Hôpital de la Mère et de l'enfant Lagune
    Cotonou, Benin
    Not yet recruiting
  • Hôpital Robert Debré
    Paris, France
    Not yet recruiting
  • CHU de la Guadeloupe
    Pointe-à-Pitre, Guadeloupe
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.