Exploring movement differences in knee osteoarthritis and after knee replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research investigates the differences in walking and functional movement mechanics among individuals with knee osteoarthritis, those who have undergone total knee replacement, and healthy individuals. It aims to understand how these differences affect exercise response and physical activity levels. The study will analyze the impact of pain, stiffness, and joint instability on physical activity, as well as the potential reasons why joint replacement may not lead to improved activity levels. Findings from this observational study could inform future interventions to enhance clinical outcomes and quality of life for affected individuals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed symptomatic bilateral or unilateral knee osteoarthritis, self-reported ability to walk without an aid for 10 minutes and to ascend and descend stairs, no neurological conditions or other musculoskeletal pathology/injury which would impact walking gait.

Exclusion Criteria:

* Unable to walk at 0.8 m/s, exclusion based on IMO screening, non-English speaking, lacking ability to consent.

Where it's running

• School of Psychology, Health and Sport Sciences, University of Portsmouth
  Portsmouth, Hampshire, United Kingdom Recruiting

Study contacts

• Study coordinator: Josie Morris, BSc
• Email: josie.morris@port.ac.uk
• Phone: 02392 846395

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Autologous adipose-derived stem cell injections for knee osteoarthritis

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• Preoperative Multimorbidity and Functional Recovery After Total Knee Arthroplasty

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• Cartilage biomarker response to acute loading in knee OA by antiresorptive treatment status

  Researchers will test whether a 30-minute treadmill walk changes cartilage biomarkers in postmenopausal women with knee osteoarthritis, comparing those on denosumab, bisphosphonates, and those not on antiresorptives.

  Recruiting Sisli Hamidiye Etfal Training and Research Hospital · Istanbul, Istanbul · NCT07881861

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.