Exploring how synbiotics can modify the microbiota in newborns exposed to antibiotics

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates whether administering a synbiotic supplement to newborns exposed to antibiotics at birth can alter their microbiota and potentially lower the risk of obesity and chronic diseases. A total of 125 mother-child pairs will be enrolled in a randomized, double-blind, placebo-controlled design, where infants will receive either the synbiotic or a placebo for two months. Following the intervention, the growth and health of the infants will be monitored for two years to assess the long-term effects of the treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Pregnant women (n=125) and their newborn children who receive antibiotic treatment at delivery.

Exclusion Criteria:

* Chorioamnionitis
* Pre-eclampsia and hepatogestosis
* Suspected malformation or serious condition of the foetus and neonates
* Serious infection or other conditions not permitting breast milk feeding

Where it's running

• Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku
  Turku, Valitse Maakunta., Finland Recruiting

Study contacts

• Study coordinator: Paula Tähtinen, MD, PhD
• Email: paula.tahtinen@utu.fi
• Phone: +358-2-3130746

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.