Exploring how motivation affects learning through a treasure task
Official title: The Influence of Mesolimbic-hippocampal Interactions on Episodic Memory During Active Information Seeking
Run by Temple University · NCT06257433 · Data updated 2026-11-12
This study tests how motivation impacts learning by having participants play a treasure hunt game while their brain activity is monitored.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Temple University Academic / other |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Status | Recruiting |
| Started | October 24, 2023 |
| Main results expected | August 1, 2026 |
| Study ends | August 1, 2026 |
| Registry record updated | September 5, 2025 |
| Trial ID | NCT06257433 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy adults aged 18 and older with normal or corrected vision.
✕Probably not a fit
Patients with a history of head injury, central nervous system illnesses, or those on medications affecting alertness may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the relationship between motivation and learning by having participants engage in a treasure task during neuroimaging. Participants will select from three keys to determine which feature unlocks a treasure chest, revealing unique images. The task is designed to manipulate goal-oriented exploration and uncertainty resolution by changing the target feature of the key after successful attempts. Participants will complete multiple runs of hypothesis testing and control tasks to assess their learning and decision-making processes.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of motivation's role in learning, potentially leading to improved strategies for educational and therapeutic interventions.
How similar studies have gone: While the specific approach of this study is novel, similar studies exploring motivation and learning have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 20/40 far acuity (either corrected or uncorrected) * In good medical health Exclusion Criteria: * History of head injury * History of illness with Central Nervous Systems implications * On Medications that Affect blood flow response and alertness * Consumption of smoking and/or coffee 30 minutes prior to laboratory testing * Placement of a device contraindicated for magnetic resonance imaging including cardia pacemaker, aneurysm clip, cochlear implants, pregnancy, intra-uterine device, shrapnel, metal fragments in the eyes, neurostimulators * Weight \> 250lbs * Claustrophobia
Where it's running
-
Temple University
Philadelphia, Pennsylvania, United States Recruiting
Study contacts
- Study coordinator: Vishnu Murty, PhD
- Email: vishnu.murty@temple.edu
- Phone: 7406328932
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.