Exploring how insomnia affects health and fitness
Insomnia´s Impact on DNA Stability, Cardio-metabolic Health and Lifestyle Behaviors: A Case-control Study
This study looks at how insomnia affects health and fitness in different groups of people to see what impact it has on things like body composition and exercise ability.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Universidad Autonoma de Baja California Academic / other |
| Locations | 1 site (Ensenada, Estado de Baja California) |
| Trial ID | NCT06869486 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the impact of insomnia on various health parameters, including body composition, cardiorespiratory fitness, and metabolic flexibility. It focuses on different populations, such as healthy individuals, athletes, older adults, university students, and those with metabolic syndrome, to understand the biological and environmental factors contributing to insomnia's prevalence and health consequences. The study employs various methodologies, including exercise interventions, bioelectrical impedance analysis, and micronucleus assays, to assess the relationship between insomnia and health outcomes. By analyzing these associations, the research aims to inform effective prevention and intervention strategies for insomnia-related health issues.
Who should consider this trial
Good fit: Ideal candidates include healthy individuals, athletes, older adults, university students, and individuals with metabolic syndrome aged 18-75.
Not a fit: Patients with severe cognitive or mental health disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for managing insomnia and its associated health risks, enhancing overall patient well-being.
How similar studies have performed: Other studies have shown significant associations between insomnia and health outcomes, suggesting that this approach is supported by existing research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Each population group will meet the following inclusion criteria: * Healthy Individuals (18-35 years old, men and women) * Waist circumference: \<90 cm (men), \<80 cm (women) * Fasting glucose: 70-110 mg/dL * Blood pressure: \<120/80 mmHg * Triglycerides: \<150 mg/dL * HDL-C: \>40 mg/dL (men), \>50 mg/dL (women) * Physical activity level: 600-1500 MET-min/week * Athletes (18-35 years old, men and women) \*Engaged in structured sports training with a physical activity level \>1500 MET-min/week * Older Adults (65-75 years old, men and women) \*Free of cognitive or mental health disorders. No specific cardiometabolic or body composition criteria due to the study's exploratory nature. * University Students (18-35 years old, men and women) \*No specific cardiometabolic or body composition criteria due to the study's exploratory nature. * Individuals with Metabolic Syndrome (18-35 years old, men and women) * Waist circumference: \>90 cm (men), \>80 cm (women) * Fasting glucose: \>110 mg/dL * Blood pressure: \>130/80 mmHg * Triglycerides: \>150 mg/dL * HDL-C: \<40 mg/dL (men), \<50 mg/dL (women) * Physical activity level: \<600 MET-min/week Exclusion Criteria: * Individuals with respiratory diseases or musculoskeletal injuries that prevent exercise, as determined by a clinical history review, a physical activity readiness questionnaire (PART-Q+), and pulmonary function tests (spirometry). Individuals with rotating or night-shift work schedules (e.g., emergency personnel, security guards), as circadian rhythm disruptions significantly impact sleep quality * Women diagnosed with polycystic ovary syndrome (PCOS) or showing high testosterone levels with a history of oligomenorrhea, as these conditions may influence metabolic and hormonal markers. However, women with menstrual irregularities related to premenstrual syndrome (PMS) or dysmenorrhea will not be excluded, given the established link between sleep disorders and menstrual cycle variations * This study does not involve chronic dietary or exercise interventions, nor does it require long-term participant follow-up, so no additional exclusion criteria apply
Where this trial is running
Ensenada, Estado de Baja California
- Laboratorio de Fisiologia Aplicada al Ejercicio — Ensenada, Estado de Baja California, Mexico (Recruiting)
Study contacts
- Principal investigator: Isaac A Chavez-Guevara, PhD — Universidad Autonoma de Baja California
- Study coordinator: Ivan Renteria, PhD
- Email: irenteria@uabc.edu.mx
- Phone: +52 646 152 823
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.