Clinical trial Recruiting at 1 site Interventional Ages 40 to 80

Exploring how brain injuries affect mental time travel abilities

Official title: How Self-processing Affects Mental Time Travel: a Neuropsychological Study

Run by Istituti Clinici Scientifici Maugeri SpA · NCT06823193 · Data updated 2026-11-12

This study is trying to see how brain injuries affect people's ability to remember the past and imagine the future.

Quick facts

Study typeInterventional
Ages40 Years to 80 Years
SexAll
Enrollment66 (estimated)
SponsorIstituti Clinici Scientifici Maugeri SpA
Academic / other
Locations1 site (Castel Goffredo, Mantova)
StatusRecruiting
StartedDecember 1, 2024
Main results expectedDecember 30, 2026
Study endsJune 30, 2027
Registry record updatedNovember 4, 2026
Trial IDNCT06823193 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals with focal brain lesions but without general cognitive impairment.

Probably not a fit

Patients with psychiatric disorders or multiple brain lesions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the role of the ventromedial prefrontal cortex in mental time travel (MTT), which is the ability to project oneself into past or future events. It focuses on patients with focal brain lesions and utilizes tasks such as mental time travel, age estimation, and lifeline tasks to assess cognitive functions. The research aims to understand how specific brain areas contribute to the ability to remember past events and imagine future scenarios, particularly in individuals with brain injuries.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of cognitive rehabilitation strategies for patients with brain injuries.

How similar studies have gone: Other studies have shown promising results in understanding the neural correlates of mental time travel, suggesting that this approach has a foundation in existing research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* the absence of general cognitive impairment, assessed by neuropsychological testing
* the presence of a focal brain lesion will be adopted as an inclusion criterion for patients.

Exclusion Criteria:

* psychiatric disorders
* multiple brain lesions

Where it's running

  • Istituti Clinici Scientifici Maugeri
    Castel Goffredo, Mantova, Italy
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.