Exploring how brain injuries affect mental time travel abilities
Official title: How Self-processing Affects Mental Time Travel: a Neuropsychological Study
Run by Istituti Clinici Scientifici Maugeri SpA · NCT06823193 · Data updated 2026-11-12
This study is trying to see how brain injuries affect people's ability to remember the past and imagine the future.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 80 Years |
| Sex | All |
| Enrollment | 66 (estimated) |
| Sponsor | Istituti Clinici Scientifici Maugeri SpA Academic / other |
| Locations | 1 site (Castel Goffredo, Mantova) |
| Status | Recruiting |
| Started | December 1, 2024 |
| Main results expected | December 30, 2026 |
| Study ends | June 30, 2027 |
| Registry record updated | November 4, 2026 |
| Trial ID | NCT06823193 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals with focal brain lesions but without general cognitive impairment.
✕Probably not a fit
Patients with psychiatric disorders or multiple brain lesions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the role of the ventromedial prefrontal cortex in mental time travel (MTT), which is the ability to project oneself into past or future events. It focuses on patients with focal brain lesions and utilizes tasks such as mental time travel, age estimation, and lifeline tasks to assess cognitive functions. The research aims to understand how specific brain areas contribute to the ability to remember past events and imagine future scenarios, particularly in individuals with brain injuries.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of cognitive rehabilitation strategies for patients with brain injuries.
How similar studies have gone: Other studies have shown promising results in understanding the neural correlates of mental time travel, suggesting that this approach has a foundation in existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * the absence of general cognitive impairment, assessed by neuropsychological testing * the presence of a focal brain lesion will be adopted as an inclusion criterion for patients. Exclusion Criteria: * psychiatric disorders * multiple brain lesions
Where it's running
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Istituti Clinici Scientifici Maugeri
Castel Goffredo, Mantova, Italy Recruiting
Study contacts
- Principal investigator: Giuliana Vezzadini, MD — Istituti Clinici Scientifici Maugeri
- Study coordinator: Giuliana Vezzadini, MD
- Email: giuliana.vezzadini@icsmaugeri.it
- Phone: 0376-7741
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.