Exploring genetic factors in neuropathic pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify new genetic variants associated with the development of neuropathic pain, a condition affecting 7-8% of the general population. By utilizing existing population-based cohorts and establishing a registry and biobank for patients with neuropathy, the researchers will conduct genetic association studies to uncover molecular mechanisms underlying neuropathic pain. The study will involve international collaboration to ensure a large and diverse patient population, enhancing the reliability of the findings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. The patient is between 18 and 70 years old.
2. The patient has consented.
3. The patient is referred for evaluation of possible distal symmetric polyneuropathy (DSPN).
4. The patient has filled out the questionnaires.

Exclusion Criteria:

1. The patient is too sick to participate (eg. bedridden, fever).
2. The patient is unable to consent (eg. dementia, speech problems, psychiatric disorder).
3. Inflammatory acute polyneuropathy.

Where it's running

• Haukeland University Hospital
  Bergen, Norway Recruiting
• Oslo University Hospital
  Oslo, Norway Recruiting
• Helse Stavanger HF
  Stavanger, Norway Recruiting
• University Hospital of North Norway
  Tromsø, Norway Recruiting
• St. Olavs Hospital
  Trondheim, Norway Recruiting

Study contacts

• Principal investigator: David Benett, M.D. — University of Oxford
• Study coordinator: Kristian B. Nilsen, M.D
• Email: uxnikq@ous-hf.no
• Phone: +4791372241

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.