Clinical trial Recruiting at 1 site Observational Ages 18 to 99

Exploring genetic factors in gallbladder cancer treatment responses

Official title: Genetic Mutations and Response to Treatment in Gallbladder Cancer: A Hospital Based Cohort Study

Run by Banaras Hindu University · NCT05404347 · Data updated 2026-11-12

This study is trying to see how certain genetic changes in people with gallbladder cancer affect how well they respond to treatment.

Quick facts

Study typeObservational
Ages18 Years to 99 Years
SexAll
Enrollment100 (estimated)
SponsorBanaras Hindu University
Academic / other
Drugs / interventionsradiation
Locations1 site (Varanasi, Uttar Pradesh)
StatusRecruiting
StartedJanuary 1, 2018
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedAugust 13, 2024
Trial IDNCT05404347 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are treatment-naïve patients with histologically proven gallbladder carcinoma.

Probably not a fit

Patients without histological evidence of malignancy or those who are pregnant or lactating may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the genetic mutations associated with gallbladder cancer and their potential impact on treatment responses. By utilizing next-generation sequencing, the study aims to identify key oncogenes and tumor suppressor genes that may influence patient outcomes. The research focuses on treatment-naïve patients with histologically confirmed gallbladder carcinoma, aiming to bridge the gap between genetic profiling and personalized treatment strategies. The findings could provide insights into the molecular mechanisms driving gallbladder cancer and inform future therapeutic approaches.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective treatment options for patients with gallbladder cancer based on their genetic profiles.

How similar studies have gone: While there have been promising clinical trials in other cancers utilizing genetic profiling, the application of these principles in gallbladder cancer remains largely unexplored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Treatment naïve patients with histologically proven carcinoma of the gallbladder.

Exclusion Criteria:

* No histological evidence of malignancy
* Pregnant and lactating women

Where it's running

  • Banaras Hindu University
    Varanasi, Uttar Pradesh, India
    Recruiting

Study contacts

  • Principal investigator: Manoj Pandey, Ms, PhD — Banaras Hindu University
  • Study coordinator: Manoj Pandey, MS, PhD
  • Email: mpandey66@bhu.ac.in
  • Phone: 2361014

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.