Home › Trials › NCT06192719

Identifying risk factors for gallbladder cancer and gallstone disease

Establishment and Exploitation of a European-Latin American Research Consortium Towards Eradication of Preventable Gallbladder Cancer - EULAT Eradicate GBC

Observational Centre Paul Strauss · NCT06192719

This study is trying to find out what causes gallbladder cancer and gallstone disease by looking at different lifestyle and genetic factors to help with early detection and prevention.

Quick facts

Study typeObservational
Enrollment15000 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Paul Strauss Academic / other
Locations36 sites (Salta and 35 other locations)
Trial IDNCT06192719 on ClinicalTrials.gov

What this trial studies

This observational study focuses on gallbladder cancer (GBC) and gallstone disease, aiming to improve early detection and risk estimation for GBC. Researchers will analyze various epidemiological factors, including geographical, environmental, lifestyle, and genetic influences, to develop a multifactorial risk score. The study will also create a biorepository and an IT platform to facilitate the identification and validation of novel GBC biomarkers. By understanding the causal mechanisms linking lifestyle and GBC, the study seeks to enhance prevention strategies and guide clinical decisions regarding gallbladder removal.

Who should consider this trial

Good fit: Ideal candidates include men and women aged 18 or over with gallbladder cancer, dysplasia, or scheduled for cholecystectomy due to gallstones.

Not a fit: Patients with medical or psychiatric conditions that interfere with informed consent or pose unreasonable risks will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection and prevention strategies for gallbladder cancer, potentially saving lives.

How similar studies have performed: While there have been studies focusing on gallbladder cancer, this approach of integrating multifactorial risk assessments and creating a biorepository is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

1. Cohort A. Patients with gallbladder cancer or dysplasia, both before and after the start of their anticancer treatment.

   Cohort B. Patients with cholelithiasis before cholecystectomy (only patients scheduled for cholecystectomy will be recruited)
2. Diagnosis confirmed in accordance with standard protocols of the participating hospitals
3. Men and women aged 18 or over

Exclusion Criteria:

1. Any medical condition that present an unreasonable risk to the participant.
2. Any psychiatric condition that interferes with understanding informed consent.

Where this trial is running

Salta and 35 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Gallbladder CancerGallstone Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.