Exploring cognitive impairment and eye health in elderly individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on elderly individuals with cerebral small vessel disease who do not have known dementia or stroke. Participants will undergo neuropsychological testing, retinal imaging, and multimodal MRI to assess brain changes over time. The study aims to identify predictors of disease progression and cognitive deficits by analyzing various brain and retinal features. Blood samples will also be collected to further understand the relationship between these conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult (≥40y; no upper limit)
* Free of known dementia or stroke (both cerebral infarction and hemorrhage)

Exclusion Criteria:

* Any MRI contraindications
* Serious head injury (resulting to loss of consciousness) or received intracranial surgery
* Suffering from cancer

Where it's running

• The second affiliated hospital of Zhejiang University
  Hangzhou, China Recruiting

Study contacts

• Study coordinator: Min Lou, Ph.D
• Email: loumingxc@vip.sina.com
• Phone: 13958007213

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.