Exercises to Improve Lower-Leg Blood Flow and Wound Healing
Constructing a Holistic Care New Model for Chronic Wounds and Blood Circulation Detection to Enhance Home Care Quality
This program will test whether a tailored exercise system can improve lower-leg circulation and help chronic wounds in older adults with poor peripheral blood flow.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 425 (estimated) |
| Ages | 20 Years to 95 Years |
| Sex | All |
| Sponsor | National Health Research Institutes, Taiwan Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT07330635 on ClinicalTrials.gov |
What this trial studies
This interventional project develops a lower-limb circulation enhancement exercise system and compares three exercise approaches: a mixed exercise program, high-intensity rowing, and vibration exercise. The trial enrolls young healthy controls, healthy older adults (65–95), and older adults with chronic diseases that impair peripheral circulation. Outcomes include measures of lower-limb blood flow and functional performance, with exercises adapted for participants' frailty and ability. Participants must be able to perform basic physical activity and provide informed consent for in-person assessments.
Who should consider this trial
Good fit: Ideal candidates are adults aged 65–95 with impaired peripheral circulation (for example from peripheral arterial disease, chronic venous insufficiency, diabetes, hypertension, or hyperlipidemia) who can perform basic physical activity and provide informed consent.
Not a fit: People who are too physically frail to perform exercise, have unstable medical conditions or acute limb-threatening events, or have severe cognitive impairment are unlikely to receive benefit from these interventions.
Why it matters
Potential benefit: If successful, the program could improve leg blood flow, speed healing of chronic wounds, reduce reliance on medications, and improve mobility and quality of life for older adults.
How similar studies have performed: Prior research shows exercise programs can improve peripheral circulation and walking function in older adults, though high-intensity rowing and vibration approaches are less well studied in frail elderly populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: General criteria (applied to all participants): Willingness to participate in this study and comply with all study procedures. Able to perform basic physical activity and complete lower limb circulatory and functional assessments. Normal cognitive function sufficient to understand instructions and provide informed consent. Group-specific criteria: Young Adults (Control Group):Aged 20-40 years.No known chronic diseases or peripheral circulatory disorders.Considered healthy volunteers. Older Adults (Healthy Elderly Group):Aged 65-95 years.No major chronic diseases affecting lower limb circulation. Older Adults with Chronic Disease (Impaired Circulation Group):Aged 65-95 years.Diagnosed with one or more conditions known to impair peripheral circulation, including but not limited to peripheral arterial disease (e.g., atherosclerosis, thromboangiitis obliterans), chronic venous insufficiency (e.g., varicose veins), diabetes mellitus, hypertension, or hyperlipidemia. Exclusion Criteria: Recent acute lower limb injury resulting in tissue exudation, swelling, or other conditions that prevent safe participation in the assessment or intervention procedures.
Where this trial is running
Taipei
- National Center for Geriatrics and Welfare Research, National Health Research Institutes — Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Po-Jung Chen, Ph.D.
- Email: pojungchen@nhri.edu.tw
- Phone: +886-5-632-5080
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.