Exercise therapy to improve blood cell function in hemodialysis patients
Effects of Supervised Exercise on Rheological Functions of Erythrocyte in Patients With End-Stage Renal Disease on Hemodialysis
This study is testing if a supervised exercise program can help improve blood cell function and overall quality of life for people on hemodialysis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 180 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | Chang Gung Memorial Hospital Academic / other |
| Locations | 1 site (Taoyuan) |
| Trial ID | NCT06575634 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance aerobic capacity, muscular function, and quality of life in patients with end-stage renal disease (ESRD) through supervised exercise training. Participants will engage in exercise therapy three times a week for six months, initially in a hospital setting and later at home. The study will assess the impact of this exercise on erythrocyte rheological properties, including red blood cell deformability and aggregation, using advanced measurement techniques. Cardiopulmonary exercise tests will be conducted before and after the intervention to evaluate improvements in fitness levels.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 20 years old who have been receiving hemodialysis for at least six weeks.
Not a fit: Patients with orthopedic or muscular diseases, or those with contraindications to exercise, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the physical health and quality of life for patients undergoing hemodialysis.
How similar studies have performed: Previous studies have shown positive outcomes with supervised exercise interventions in hemodialysis patients, suggesting this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Receiving hemodialysis and medication at least for 6 weeks * Kt/V score \> 1.2 Exclusion Criteria: * Under 20 years-old * Hyperkalemia occurs within 3 month * Having orthopedic or muscular diseases * Other concerned medical, psychological or physiological diseases * Pregnancy * Other exercise contraindications
Where this trial is running
Taoyuan
- Chang Gung University — Taoyuan, Taiwan (Recruiting)
Study contacts
- Principal investigator: Jong-Shyan Wang, PhD — Chang Gung Memorial Hospital
- Study coordinator: Jong-Shyan Wang, PhD
- Email: s5492@mail.cgu.edu.tw
- Phone: +886-3-2118800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.